更大的外侧前额叶皮质体积预示着老年女性更好的运动依从性：来自两项运动训练研究的证据。

Larger Lateral Prefrontal Cortex Volume Predicts Better Exercise Adherence Among Older Women: Evidence From Two Exercise Training Studies.

机构信息

Djavad Mowafaghian Centre for Brain Health and.

Department of Physical Therapy, University of British Columbia, Vancouver, Canada.

出版信息

J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):804-810. doi: 10.1093/gerona/glx043.

DOI:10.1093/gerona/glx043

PMID:28329359

Abstract

BACKGROUND

Recent research has suggested an important role of lateral prefrontal cortex (lPFC) in consistent implementation of positive health behaviors and avoidance of negative health behaviors.

METHODS

We examined whether gray matter volume in the lPFC prospectively predicts exercise class attendance among older women (n = 122) who underwent either a 52-week or 26-week exercise training intervention. Structural magnetic resonance imaging determined gray matter volume at baseline.

RESULTS

Independent of intracranial volume, age, education, body composition, mobility, depressive symptoms, and general cognitive functioning, larger lPFC volume predicted greater exercise class attendance (all p values < .05). Follow-up whole-brain analyses further confirmed that regions in the lPFC-especially the left middle frontal gyrus (p < .005)-predicted future exercise adherence as well as identified other regions, especially in the insula and temporal cortex, that predicted exercise adherence.

CONCLUSIONS

These findings suggest that sustained engagement in exercise training might rely in part on functions of the lPFC and that lPFC volume might be a reasonable proxy for such functions.

摘要

背景

最近的研究表明，外侧前额叶皮层（lPFC）在积极实施健康行为和避免消极健康行为方面起着重要作用。

方法

我们研究了在经历 52 周或 26 周运动训练干预的老年女性（n=122）中，lPFC 的灰质体积是否能前瞻性地预测其参加运动课程的情况。结构磁共振成像在基线时确定了灰质体积。

结果

独立于颅内体积、年龄、教育程度、身体成分、活动能力、抑郁症状和一般认知功能，更大的 lPFC 体积预示着更高的运动课程出勤率（所有 p 值均<.05）。后续的全脑分析进一步证实，lPFC 中的区域——尤其是左中额回（p<.005）——可以预测未来的运动坚持情况，同时还确定了其他区域，特别是在脑岛和颞叶皮层，也可以预测运动坚持情况。