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Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis.

作者信息

Rosenstein Rachel, Martires Kathryn, Christman Mitalee, Terushkin Vitaly, Meehan Shane A, Seminara Nicole, Golden Brian D, Franks Andrew G

机构信息

Ronald O. Perelman Department of Dermatology, NYU School of Medicine, NYU Langone Medical Center.

出版信息

Dermatol Online J. 2016 Dec 15;22(12):13030/qt6qd0q51w.

Abstract

Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquired reactive perforating collagenosistypically occurs in the setting of diabetes mellitus,chronic renal failure, and other pruritic conditions,and this case represents a rare association withdermatomyositis, which may ultimately be helpful inelucidating the pathophysiology of this perforatingdisorder.

摘要

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