Department of, Dermatology, King's College Hospital NHS Foundation Trust, London, UK.
Rheumatology Department, King's College Hospital NHS Foundation Trust, London, UK.
Clin Exp Dermatol. 2021 Aug;46(6):1016-1022. doi: 10.1111/ced.14689. Epub 2021 Jun 13.
Dermatomyositis (DM) is an autoimmune connective tissue disease that is included in the idiopathic inflammatory myopathies. Cutaneous manifestations are a prominent part of the condition: some skin signs in DM are common to most patients, while other signs are encountered infrequently. A number of features are pathognomic for DM. The demonstration of myositis-specific antibodies (MSAs) in DM has extended the ability to define phenotypic subgroups. It appears that the presence of certain MSAs confers susceptibility to specific clinical features, an association which reveals a serotype-phenotype relationship. In this review article we have provided a detailed summary of common and under-recognized cutaneous manifestations of DM.
皮肌炎（DM）是一种自身免疫性结缔组织疾病，属于特发性炎症性肌病。皮肤表现是该疾病的一个突出特征：DM 中的一些皮肤征象在大多数患者中较为常见，而其他征象则很少见。许多特征是 DM 的特征性表现。DM 中肌炎特异性抗体（MSA）的检测扩展了定义表型亚组的能力。某些 MSA 的存在似乎使患者易患特定的临床特征，这种关联揭示了血清型-表型关系。在这篇综述文章中，我们详细总结了 DM 的常见和未被充分认识的皮肤表现。
