Flentje M, Kimmig B, Kuttig H, zum Winkel K
Zentrum Radiologie (Strahlenklinik), Universität Heidelberg.
Strahlenther Onkol. 1988 Mar;164(3):136-40.
Between 1968 and 1984, 61 patients with malignant parotid tumors were irradiated with fast electrons. The irradiation was performed after surgery in 58 patients, 37 out of them had tumor reresidues at the beginning of radiotherapy. The local recurrence rate was 16%, and there were no differences between patients operated in sano and patients operated non in sano. The survival at five years, however, was only 43%. This is explained by the preponderance of tumor histologies with unfavorable prognoses. Distant metastases were observed in 38% of patients. 8/10 patients with local recurrences developed distant metastases. It is noticeable that polymorphous adenomas were found in the anamneses of ten patients and histologically different secondary carcinomas in 9/61 cases.
1968年至1984年间,61例腮腺恶性肿瘤患者接受了快速电子照射。58例患者在手术后进行了照射,其中37例在放疗开始时存在肿瘤残留。局部复发率为16%,根治性手术患者与非根治性手术患者之间无差异。然而,五年生存率仅为43%。这是由于预后不良的肿瘤组织学类型占优势。38%的患者出现远处转移。8/10例局部复发患者发生了远处转移。值得注意的是,10例患者的既往病史中发现有多形性腺瘤,61例中有9例组织学上为不同的继发性癌。