Isitor G N, Kazeem H M, Njoku C O, Adegboye D S, Dellmann H D
Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
Trop Anim Health Prod. 1988 Feb;20(1):2-10. doi: 10.1007/BF02239635.
By combined electron microscopical and serological methods the rate of involvement of pox virions within lesions of bovine natural dermatophilosis was determined. Scabby lesions of 40 (77%) out of a total of 52 cases were positive for the virions, while sera of all infected animals which reacted positively for pox viral antibodies (LSD) was significantly higher (P less than 0.001) in comparison to those of healthy-appearing animals. The virions in all cases had a uniform oval to cylindrical morphology with a mean measurement of 110 X 280 nm. A synergistic interplay involving the initiation of the scabby lesions by the virions and their subsequent trapping within keratin deposits, followed by their release through the keratolytic activity of Dermatophilus congolensis appear to have obtained in cases.
通过电子显微镜和血清学相结合的方法，确定了痘病毒粒子在牛自然皮肤嗜皮菌病病变中的感染率。在总共52例病例中，40例（77%）的结痂病变中病毒粒子呈阳性，而所有对痘病毒抗体呈阳性反应（牛结节性皮炎）的感染动物血清，与外观健康的动物相比显著更高（P小于0.001）。所有病例中的病毒粒子均具有均匀的椭圆形至圆柱形形态，平均尺寸为110×280纳米。在这些病例中，似乎存在一种协同相互作用，即病毒粒子引发结痂病变，随后被困在角质沉积物中，接着通过刚果嗜皮菌的角质溶解活性释放出来。
