Shen H C, Huang S J, Qin X L, Zhao P Z, Lan Y Y, Zou H C, Ou J L, Chen L, Luo X M, Zheng H P, Li Y, Yang B
Dermatology Hospital of Southern Medical University/Guangdong Provincial Dermatology Hospital, Guangzhou 510095, China.
Guangdong Pharmaceutical University, Guangzhou 510310, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Mar 10;38(3):364-368. doi: 10.3760/cma.j.issn.0254-6450.2017.03.018.
To investigate the prevalence of genital (GCT) infection and associated risk factors in male clients attending sexually transmitted disease (STD) clinics in Guangdong and provide integrated intervention strategy for this group. Convenient sampling was used to recruit participants from April to June in 2015 in Guangdong province. The information about their socio-demographic characteristics and sexual behaviors were collected by using a questionnaire, and blood samples were taken from them to test the antibodies against HIV, syphilis and HCV. First pass urine was taken to test GCT and gonorrhea. A total of 1 749 participants with the average age of 39.53 years were recruited. The majority of them were married (73.87%, 1 292/1 749), residents of Guangdong (92.28%, 1 614/1 749) and in Han ethnic group (99.49%, 1 740/1 749). The positive rates for GCT, HIV, syphilis, HCV, , and WBC in urinalysis were 6.06% (106/1 749), 0.46% (8/1 749), 3.43% (60/1 749), 0.45% (7/1 550), 2.74% (48/1 749), 7.89% (138/1 749) respectively. Multivariate analysis showed that risk factors for GCT infection include IDUs (=13.98, 95: 3.35-58.38), anal sex with men (=3.11, 95: 1.45-6.71), positive (=9.64, 95: 5.09-18.24), and WBC positive (=1.96, 95: 1.08-3.55). This study demonstrated the high prevalence of GCT infection in male clients attending STD clinics in Guangdong. Therefore precision intervention should target this population at high-risk.
调查广东省性病门诊男性就诊者中生殖支原体（GCT）感染的流行情况及其相关危险因素，并为该群体提供综合干预策略。2015年4月至6月在广东省采用方便抽样法招募研究对象。通过问卷调查收集其社会人口学特征和性行为等信息，并采集血样检测HIV、梅毒和丙肝病毒抗体。采集首次晨尿检测生殖支原体和淋病。共招募1749名研究对象，平均年龄39.53岁。其中大多数已婚（73.87%，1292/1749），为广东居民（92.28%，1614/1749），汉族（99.49%，1740/1749）。生殖支原体、HIV、梅毒、丙肝病毒、淋球菌及尿白细胞阳性率分别为6.06%（106/1749）、0.46%（8/1749）、3.43%（60/1749）、0.45%（7/1550）、2.74%（48/1749）、7.89%（138/1749）。多因素分析显示，生殖支原体感染的危险因素包括注射吸毒（比值比=13.98，95%可信区间：3.35～58.38）、男性同性肛交（比值比=3.11，95%可信区间：1.45～6.71）、淋球菌阳性（比值比=9.64，95%可信区间：5.09～18.24）及尿白细胞阳性（比值比=1.96，95%可信区间：1.08～3.55）。本研究显示广东省性病门诊男性就诊者生殖支原体感染率较高。因此，应针对该高危人群进行精准干预。
