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从铜绿假单胞菌菌株BTRY1中分离出的具有自由基清除和抗生物膜特性的绿脓菌素的特性分析。

Characterization of pyocyanin with radical scavenging and antibiofilm properties isolated from Pseudomonas aeruginosa strain BTRY1.

作者信息

Laxmi M, Bhat Sarita G

机构信息

Department of Biotechnology, Cochin University of Science and Technology, Kochi, 682022, Kerala, India.

出版信息

3 Biotech. 2016 Jun;6(1):27. doi: 10.1007/s13205-015-0350-1. Epub 2016 Jan 11.

Abstract

A biomolecule namely pyocyanin was isolated from Pseudomonas aeruginosa (BTRY1). It was confirmed by UV-Vis spectrum with absorption maxima at 270 nm and was further characterized using Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR). Spectroscopy analyses showed the presence of relevant bonds in their respective structures. Although pyocyanin had antihemolytic, antioxidant and antibiofilm activities against food pathogens, it showed no observable cytotoxicity, and thus proposed for potential use in the preservation of food.

摘要

从铜绿假单胞菌(BTRY1)中分离出一种生物分子——绿脓菌素。通过紫外可见光谱确认其在270nm处有最大吸收峰,并使用傅里叶变换红外光谱(FTIR)和核磁共振(NMR)进一步表征。光谱分析表明其各自结构中存在相关键。尽管绿脓菌素对食品病原体具有抗溶血、抗氧化和抗生物膜活性,但未观察到细胞毒性,因此建议将其用于食品保鲜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89fe/4711285/b548fa9d8355/13205_2015_350_Fig1_HTML.jpg

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