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一项前瞻性观察性研究,旨在评估社会和人格因素对阻塞性睡眠呼吸暂停综合征患者持续气道正压通气(CPAP)依从性的影响。

A prospective observational study to evaluate the effect of social and personality factors on continuous positive airway pressure (CPAP) compliance in obstructive sleep apnoea syndrome.

作者信息

Gulati Atul, Ali Masood, Davies Mike, Quinnell Tim, Smith Ian

机构信息

Consultant respiratory medicine, New Cross Hospital, Heath Road, Wolverhampton, West Midlands, WV10 0QP, UK.

Consultant respiratory medicine, Southend University Hospital, Prittlewell Chase, Westcliffe on Sea, Essex, SS0 0RY, UK.

出版信息

BMC Pulm Med. 2017 Mar 22;17(1):56. doi: 10.1186/s12890-017-0393-7.

Abstract

BACKGROUND

Compliance with CPAP treatment for OSAS is not reliably predicted by the severity of symptoms or physiological variables. We examined a range of factors which could be measured before CPAP initiation to look for predictors of compliance.

METHODS

This was a prospective cohort-study of CPAP treatment for OSAS, recording; socio-economic status, education, type D personality and clinician's prediction of compliance.

RESULTS

We recruited 265 subjects, of whom 221 were still using CPAP at 6 months; median age 53 years, M: F, 3.4:1, ESS 15 and pre-treatment ODI 21/h. Median compliance at 6 months was 5.6 (3.4- 7.1) hours/night with 73.3% of subjects using CPAP ≥4 h/night. No association was found between compliance and different socio-economic classes for people in work, type D personality, education level, sex, age, baseline ESS or ODI. The clinician's initial impression could separate groups of good and poor compliers but had little predictive value for individual patients. Compared to subjects who were working, those who were long term unemployed had a lower CPAP usage and were more likely to use CPAP < 4 h a night (OR 4.6; p value 0.011). A high Beck Depression Index and self-reported anxiety also predicted poor compliance.

CONCLUSIONS

In our practice there is no significant association between CPAP compliance with socio-economic status, education or personality type. Long term unemployed or depressed individuals may need more intensive support to gain the optimal benefit from CPAP.

摘要

背景

阻塞性睡眠呼吸暂停低通气综合征(OSAS)患者对持续气道正压通气(CPAP)治疗的依从性无法通过症状严重程度或生理变量可靠预测。我们研究了一系列在开始CPAP治疗前可测量的因素,以寻找依从性的预测指标。

方法

这是一项关于OSAS患者CPAP治疗的前瞻性队列研究,记录社会经济状况、教育程度、D型人格以及临床医生对依从性的预测。

结果

我们招募了265名受试者,其中221人在6个月时仍在使用CPAP;中位年龄53岁,男性与女性比例为3.4:1,Epworth嗜睡量表(ESS)评分为15分,治疗前夜间血氧饱和度低于90%的次数(ODI)为21次/小时。6个月时的中位依从性为5.6(3.4 - 7.1)小时/晚,73.3%的受试者每晚使用CPAP≥4小时。在在职人员中,依从性与不同社会经济阶层、D型人格、教育水平、性别、年龄、基线ESS或ODI之间未发现关联。临床医生的初始印象可区分依从性好和差的群体,但对个体患者的预测价值不大。与在职受试者相比,长期失业者的CPAP使用时间较短,且更有可能每晚使用CPAP<4小时(比值比4.6;p值0.011)。贝克抑郁量表得分高和自我报告的焦虑也预示着依从性差。

结论

在我们的实践中,CPAP依从性与社会经济状况、教育程度或人格类型之间无显著关联。长期失业或抑郁的个体可能需要更多强化支持,以从CPAP中获得最佳益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc22/5361817/253a45f5b3b0/12890_2017_393_Fig1_HTML.jpg

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