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伪装成神经鞘瘤的原发性椎体平滑肌肉瘤。

Primary vertebral leiomyosarcoma masquerading as a nerve sheath tumour.

作者信息

Ahmad Irfan, Goyal Nidhi, Bhatt Chandi Prasad, Chufal Kundan Singh

机构信息

Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.

Department of Radiodiagnosis, Gulati Imaging Institute, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2017 Mar 22;2017:bcr2016217602. doi: 10.1136/bcr-2016-217602.

Abstract

A 47-year-old woman presented with symptoms of low back pain and weakness in bilateral lower limbs. MRI of the spine revealed a mass arising from T11 vertebra involving neural foramina at bilateral T11-12 and right T10-11 levels with extension to the right paravertebral region. Suspecting a nerve sheath tumour, she underwent posterior spinal decompression, stabilisation and debulking, following which her neurological symptoms resolved. Histopathological and immunohistochemical evaluation revealed a leiomyosarcoma. A month later she developed sudden paraparesis and MRI revealed an increase in size of the tumour with cord compression and displacement. She underwent a repeat spinal decompression and debulking procedure after which she received adjuvant radiotherapy via volumetric modulated arc therapy, to a total dose of 45 Gy in 25 fractions over 5 weeks. MRI performed 2 months later revealed complete response and she is disease free for the past 5 months.

摘要

一名47岁女性出现腰痛及双下肢无力症状。脊柱MRI显示一个肿块起源于T11椎体,累及双侧T11 - 12及右侧T10 - 11水平的神经孔,并延伸至右侧椎旁区域。怀疑为神经鞘瘤,她接受了后路脊柱减压、固定及减瘤手术,术后神经症状缓解。组织病理学和免疫组化评估显示为平滑肌肉瘤。一个月后她突然出现双下肢轻瘫,MRI显示肿瘤增大并压迫和移位脊髓。她接受了再次脊柱减压和减瘤手术,之后通过容积调强弧形放疗接受辅助放疗,总剂量45 Gy,分25次,在5周内完成。2个月后进行的MRI显示完全缓解,在过去5个月里她无疾病复发。

相似文献

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Primary leiomyosarcoma of the spine.脊柱原发性平滑肌肉瘤
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本文引用的文献

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MR Imaging Findings of a Leiomyosarcoma of the Thoracic Spine: A Case Report.
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Radiation dose-volume effects in the spinal cord.脊髓的辐射剂量-体积效应。
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S42-9. doi: 10.1016/j.ijrobp.2009.04.095.
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