Ido K, Matsuoka H, Yoshida M, Urushidani H
Department of Orthopaedic Surgery, Kurashiki Central Hospital, Japan.
J Clin Neurosci. 2002 May;9(3):325-8. doi: 10.1054/jocn.2001.0989.
We present an 83-year-old man who developed three different leiomyosarcoma lesions in the thigh, back, and thoracic spine. The pathology of the thigh tumour was pleomorphic leiomyosarcoma. MRI after 4 years showed a vertebral bone lesion associated with spinal cord compression at T7 and a paravertebral mass lesion at T9-T10. Surgical treatment for the spinal lesion which caused paraparesis improved the neurological symptoms. The pathological features of the lesions in the back and spine were identical and rather distinct from those of the previous thigh lesion. Spinal leiomyosarcoma causing paraparesis and the two other with soft-tissue leiomyosarcoma lesions with different pathological features in a single patient over a period of 4 years is an extremely rare occurrence.
我们报告一名83岁男性，其在大腿、背部和胸椎处出现了三种不同的平滑肌肉瘤病变。大腿肿瘤的病理类型为多形性平滑肌肉瘤。4年后的MRI显示T7椎体骨病变伴脊髓受压，T9 - T10有椎旁肿块病变。对导致轻截瘫的脊柱病变进行手术治疗后神经症状得到改善。背部和脊柱病变的病理特征相同，与之前大腿病变的病理特征明显不同。在4年时间里，一名患者出现导致轻截瘫的脊柱平滑肌肉瘤以及另外两处具有不同病理特征的软组织平滑肌肉瘤病变，这种情况极为罕见。
