多发性硬化症患者对疾病修正疗法依从性的社会心理预测因素。
Psychosocial predictors of patient adherence to disease-modifying therapies for multiple sclerosis.
作者信息
Alosaimi Fahad D, AlMulhem Alaa, AlShalan Hanan, Alqazlan Mohammad, Aldaif Abdulgader, Kowgier Matthew, Balasundaram Janooshsheya, Sockalingam Sanjeev
机构信息
Department of Psychiatry.
College of Medicine, King Saud University.
出版信息
Patient Prefer Adherence. 2017 Mar 9;11:513-518. doi: 10.2147/PPA.S129678. eCollection 2017.
OBJECTIVES
Our aim was to identify the impact of psychosocial predictors, specifically relationship style, depressive symptoms, anxiety symptoms, cognitive impairment, and culture-specific disease beliefs, on treatment adherence for multiple sclerosis (MS) patients.
METHODS
In this cross-sectional observational study, patients from two MS clinics in Saudi Arabia completed self-reported questionnaires focused on MS treatment adherence, physical symptom burden, relationship style, cultural beliefs, depressive symptoms, anxiety, and cognitive impairment.
RESULTS
A total of 163 MS patients participated, 81.6% of them were female, and the mean age of the patients was 31.6 years. Mean patient-reported adherence to their MS treatment regimen was 79.47%±25.26%. Multivariate linear regression analysis only identified patients' belief that their MS was due to "supernatural" forces as being significantly negatively associated with MS medication adherence.
CONCLUSION
This study demonstrates the importance of cultural interpretations to MS medication adherence in comparison to psychosocial factors. Education and family involvement in the treatment planning may address this issue and warrant further research.
目的
我们的目的是确定心理社会预测因素，特别是人际关系风格、抑郁症状、焦虑症状、认知障碍和特定文化的疾病信念，对多发性硬化症（MS）患者治疗依从性的影响。
方法
在这项横断面观察性研究中，来自沙特阿拉伯两家MS诊所的患者完成了自我报告问卷，这些问卷聚焦于MS治疗依从性、身体症状负担、人际关系风格、文化信念、抑郁症状、焦虑和认知障碍。
结果
共有163名MS患者参与，其中81.6%为女性，患者的平均年龄为31.6岁。患者报告的MS治疗方案平均依从率为79.47%±25.26%。多变量线性回归分析仅确定患者认为其MS是由“超自然”力量导致的信念与MS药物依从性显著负相关。
结论
与心理社会因素相比，本研究证明了文化解读对MS药物依从性的重要性。教育和家庭参与治疗计划可能会解决这个问题，值得进一步研究。
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