Narita Zui, Takano Harumasa, Sumiyoshi Tomiki
Department of Psychiatry, National Center Hospital.
Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Neuropsychiatr Dis Treat. 2017 Mar 13;13:775-777. doi: 10.2147/NDT.S132516. eCollection 2017.
Neuromyelitis optica (NMO) is a relapsing disease that typically affects the spinal cord and optic nerves. So far, a few studies have reported pharmacologic treatment for psychiatric symptoms in patients with NMO spectrum disorder (NMOSD). However, no literature has described psychomotor agitation associated with the disease and its treatment. We report an 84-year-old woman with NMOSD whose psychomotor agitation was effectively treated with a combination of trazodone and risperidone. Our observation suggests the ability of augmentation of antipsychotic drugs with antidepressants to ameliorate psychotic symptoms associated with NMOSD.
视神经脊髓炎（NMO）是一种复发性疾病，通常会影响脊髓和视神经。到目前为止，已有一些研究报道了针对视神经脊髓炎谱系障碍（NMOSD）患者精神症状的药物治疗。然而，尚无文献描述该疾病及其治疗相关的精神运动性激越。我们报告了一名84岁的NMOSD女性患者，其精神运动性激越通过曲唑酮和利培酮联合治疗得到有效控制。我们的观察结果表明，抗精神病药物与抗抑郁药物联合使用能够改善与NMOSD相关的精神病性症状。
