Loong Shih Keng, Teoh Boon Teong, Johari Jefree, Khor Chee Sieng, Abd-Jamil Juraina, Nor'e Siti Sarah, Samsudin Nur Izyan, Azizan Noor Syahida, Yaacob Che Norainon, CheMatSeri Asma Anati, Mahfodz Nur Hidayana, AbuBakar Sazaly
Tropical Infectious Diseases Research & Education Centre (TIDREC), Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Tropical Infectious Diseases Research & Education Centre (TIDREC), Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia; Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Case Rep Infect Dis. 2017;2017:2578082. doi: 10.1155/2017/2578082. Epub 2017 Feb 26.
is a bacterial pathogen of major concern. The spores of this bacteria can survive harsh environmental conditions for extended periods and are well recognized as a potential bioterror weapon with significant implications. Accurate and timely identification of this species in the diagnostic laboratory is essential for disease and public health management. Biosafety Level 3 measures and ciprofloxacin treatment were instituted when was suspected from a patient with gangrenous foot. 16S rDNA sequencing was performed to accurately identify the suspected bacterium, due to the superiority of this method to accurately identify clinically isolated bacteria. was identified as the causative agent and the organism was subsequently treated as a Biosafety Level 2 pathogen.
是一种备受关注的细菌病原体。这种细菌的孢子能够在恶劣的环境条件下长时间存活，并且被公认为是一种具有重大影响的潜在生物恐怖武器。在诊断实验室中准确及时地鉴定该菌种对于疾病和公共卫生管理至关重要。当一名患有坏疽性足部的患者被怀疑感染该病菌时，采取了生物安全3级措施并使用环丙沙星进行治疗。由于16S rDNA测序在准确鉴定临床分离细菌方面具有优越性，因此进行了该测序以准确鉴定疑似细菌。该病菌被鉴定为病原体，随后该生物体被当作生物安全2级病原体进行处理。
