Kamiya H, Akhyari Payam, Minol J-P, Ites A C, Weinreich T, Sixt S, Rellecke P, Boeken U, Albert A, Lichtenberg A
Department of Cardiovascular Surgery, Medical Faculty, Heinrich Heine University Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.
Department of Cardiac Surgery, Asahikawa Medical University, 2-1-1-1, Midorigaoka Higashi, Asahikawa, 078-8510, Japan.
Gen Thorac Cardiovasc Surg. 2017 Jul;65(7):374-380. doi: 10.1007/s11748-017-0767-z. Epub 2017 Mar 22.
Current techniques for mitral valve repair (MVR) in Barlow's disease require high level of surgical expertise due to a complex anatomy. A novel and simple standardized technique that particularly considers the pathological changes of the mitral valve in Barlow's disease has been developed.
Between 2009 and 2013, 22 patients underwent minimally invasive MVR for Barlow's disease and severe mitral regurgitation (MR). A simple, standardized technique was applied, including resection of P2 segment of posterior mitral leaflet (PML) with preservation of the shortest chordae, transfer of the preserved chordae to A2, and implantation of a semi-rigid open ring. In 2015, all patients were contacted for follow-up by transthoracic echocardiography (TTE) and interviewed for their clinical status.
During follow-up (mean 2.8 ± 1.1 years; 100% complete), one patient died due to abdominal bleeding 4 months after the initial MVR and one patient with severe calcification of PML underwent valve replacement due to recurrence of MR. Among the remaining cohort (mean follow-up 3.0 ± 1.0 years), NYHA class I, II and III was present in 13, 6, and 1, respectively. TTE demonstrated MR grade 0, 1+, or 2+ in 40, 55, and 5%, respectively, with mean and maximum transvalvular gradients ranging at 1.9 ± 1.7 and 4.7 ± 3.3 mmHg, respectively.
A simple and standardized technique facilitates the repair of MR in the presence of Barlow's, simultaneously addressing the height of PML and the position of the anterior leaflet. This technique has proven durable in the mid-term follow-up in our small series and warrants further validation in larger cohorts.
由于解剖结构复杂,目前用于治疗巴洛氏病二尖瓣修复术(MVR)的技术需要高水平的手术专业知识。现已开发出一种新颖且简单的标准化技术,该技术特别考虑了巴洛氏病二尖瓣的病理变化。
2009年至2013年间,22例患有巴洛氏病和严重二尖瓣反流(MR)的患者接受了微创MVR。采用了一种简单的标准化技术,包括切除二尖瓣后叶(PML)的P2段并保留最短的腱索,将保留的腱索转移至A2,并植入半刚性开放环。2015年,通过经胸超声心动图(TTE)对所有患者进行随访,并询问其临床状况。
在随访期间(平均2.8±1.1年;随访率100%),1例患者在初次MVR后4个月因腹部出血死亡,1例PML严重钙化的患者因MR复发接受了瓣膜置换术。在其余队列中(平均随访3.0±1.0年),纽约心脏协会(NYHA)心功能分级I级、II级和III级的患者分别有13例、6例和1例。TTE显示,MR分级为0级、1+级或2+级的患者分别占40%、55%和5%,平均跨瓣压差和最大跨瓣压差分别为1.9±1.7 mmHg和4.7±3.3 mmHg。
一种简单的标准化技术有助于修复巴洛氏病患者的MR,同时解决PML的高度和前叶的位置问题。在我们的小样本系列中期随访中,该技术已证明具有持久性,值得在更大队列中进一步验证。