Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.
Clinic for Prosthodontics, Centre of Dental Specialist Care, Malmö, Sweden.
Clin Implant Dent Relat Res. 2017 Aug;19(4):632-642. doi: 10.1111/cid.12485. Epub 2017 Mar 22.
Some studies indicated that implant failures are commonly concentrated in few patients.
To identify and analyze cluster behavior of dental implant failures among subjects of a retrospective study.
This retrospective study included patients receiving at least three implants only. Patients presenting at least three implant failures were classified as presenting a cluster behavior. Univariate and multivariate logistic regression models and generalized estimating equations analysis evaluated the effect of explanatory variables on the cluster behavior.
There were 1406 patients with three or more implants (8337 implants, 592 failures). Sixty-seven (4.77%) patients presented cluster behavior, with 56.8% of all implant failures. The intake of antidepressants and bruxism were identified as potential negative factors exerting a statistically significant influence on a cluster behavior at the patient-level. The negative factors at the implant-level were turned implants, short implants, poor bone quality, age of the patient, the intake of medicaments to reduce the acid gastric production, smoking, and bruxism.
A cluster pattern among patients with implant failure is highly probable. Factors of interest as predictors for implant failures could be a number of systemic and local factors, although a direct causal relationship cannot be ascertained.
一些研究表明，种植体失败通常集中在少数患者中。
在回顾性研究的受试者中，识别和分析种植体失败的簇行为。
本回顾性研究纳入仅接受至少 3 枚种植体的患者。至少发生 3 次种植体失败的患者被归类为出现簇性行为。单变量和多变量逻辑回归模型以及广义估计方程分析评估了解释变量对簇行为的影响。
共有 1406 名患者接受了 3 个或更多种植体（8337 个种植体，592 个失败）。67 名（4.77%）患者出现簇性行为，占所有种植体失败的 56.8%。抗抑郁药和磨牙症的摄入被认为是对患者层面簇性行为产生统计学显著影响的潜在负面因素。种植体层面的负面因素为种植体转换、短种植体、骨质量差、患者年龄、减少胃酸产生的药物摄入、吸烟和磨牙症。
种植体失败患者中存在簇状模式的可能性很大。作为种植体失败预测因子的感兴趣因素可能是许多系统性和局部因素，尽管不能确定直接的因果关系。
