European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany.
Bioinformatics. 2017 Jul 15;33(14):2194-2196. doi: 10.1093/bioinformatics/btx141.
Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers.
We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks.
Dynamix is hosted at http://furlonglab.embl.de/Dynamix .
Supplementary data are available at Bioinformatics online.
基因组数据的可视化对于深入了解基因组功能至关重要。然而，在所有流行的基因组浏览器中，大量数据集的共同可视化仍然是一个挑战，需要开发新的可视化方法来提高基因组浏览器的可用性和用户体验。
我们提出了 Dynamix，这是一个 JBrowse 插件，它可以实现数百个基因组数据集的并行检查。Dynamix 利用先验知识自动显示基因组感兴趣区域内有信号的数据集。当用户浏览基因组时，Dynamix 会自动更新数据集，并限制所有手动操作，否则需要调整屏幕上可见的数据。Dynamix 还引入了一种新的轮播视图，通过允许用户独立滚动浏览组轨道，优化屏幕利用率。
Dynamix 托管在 http://furlonglab.embl.de/Dynamix 上。
补充数据可在 Bioinformatics 在线获得。
