Scarpina Federica, Mauro Alessandro, D'Aniello Guido E, Albani Giovani, Castelnuovo Gianluca, Ambiel Erika, MacPherson Sarah E
"Rita Levi Montalcini" Department of Neuroscience, University of Turin, Italy.
Psychology Research Laboratory, IRCCS Istituto Auxologico Italiano, Ospedale San Giuseppe, Piancavallo (VCO), Italy.
Arch Clin Neuropsychol. 2017 Jun 1;32(4):381-390. doi: 10.1093/arclin/acx019.
The Cognitive Estimation Test (CET) is widely used in clinical and research settings to assess the ability to produce reasonable estimates to items that individuals would not know that the exact answer (e.g., "How fast do race horses run?"). We examined the performance of non-demented Parkinson's disease (PD) patients on the CET, because previous studies reported heterogeneous results about possible cognitive estimation impairments in PD. We also examined whether PD patients improve their performance if given the chance to reconsider their initial CET responses.
Thirty non-demented idiopathic PD patients and 30 healthy controls matched in age, gender and years of education performed the two parallel forms of Italian CET. The estimation scores for initial and final responses as well as the number of times individuals changed their answers were examined. Additional neuropsychological tests, evaluating intellectual, frontal executive, speed of processing, naming and arithmetical abilities, were also administered.
The PD group were not significantly poorer than healthy controls at estimating the answers to items on either CET versions. Moreover, PD patients did not significantly differ in their initial and final responses or number of response changes. Performance on the CET was significantly related to performance on a global measure of executive function, processing speed and arithmetic. However, PD patients were impaired compared to controls on the component involving mainly, but not exclusively, length-related estimations.
Non-demented PD patients have mild impairments in cognitive estimation ability, which may depend on the estimations they are required to provide.
认知估计测试（CET）广泛应用于临床和研究环境，以评估个体对其不知道确切答案的问题做出合理估计的能力（例如，“赛马跑得多快？”）。我们研究了非痴呆帕金森病（PD）患者在CET上的表现，因为先前的研究报告了关于PD患者可能存在的认知估计障碍的异质性结果。我们还研究了如果有机会重新考虑他们最初的CET回答，PD患者的表现是否会有所改善。
30名非痴呆特发性PD患者和30名年龄、性别和受教育年限相匹配的健康对照者进行了两种平行形式的意大利语CET测试。检查了初始和最终回答的估计分数以及个体改变答案的次数。还进行了额外的神经心理学测试，以评估智力、额叶执行功能、处理速度、命名和算术能力。
在估计两个CET版本中问题的答案时，PD组并不显著差于健康对照组。此外，PD患者在初始和最终回答或回答改变次数上没有显著差异。CET上的表现与执行功能、处理速度和算术的整体测量表现显著相关。然而，与对照组相比，PD患者在主要但不限于与长度相关的估计部分存在损害。
非痴呆PD患者在认知估计能力方面存在轻度损害，这可能取决于他们需要提供的估计。
