Pasquier Christophe, Sauné Karine, Raymond Stéphanie, Boisneau Jérôme, Courtade Monique, Izopet Jacques
INSERM U1043, CPTP, CHU Purpan, BP 3028, F-31024 Toulouse, France; Université de Toulouse, UPS, CPTP, F-31024 Toulouse, France; Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France.
INSERM U1043, CPTP, CHU Purpan, BP 3028, F-31024 Toulouse, France; Université de Toulouse, UPS, CPTP, F-31024 Toulouse, France; Laboratoire de Virologie, CHU de Toulouse, Hôpital Purpan, F-31059 Toulouse, France.
Diagn Microbiol Infect Dis. 2017 Jan;87(1):25-27. doi: 10.1016/j.diagmicrobio.2016.08.022. Epub 2016 Aug 28.
Persistent infection with high-risk human papillomavirus (HPV-HR) is a recognized cause of cervical cancer. The aim of this study was to compare analytical and clinical performances of the Cobas® HPV and Anyplex™ II HPV28 assays for HPV detection and genotyping. A total of 94 cervical samples were tested. For HPV-HR, the results agreed very well (94.68%), with 100% agreement when detecting CIN2+. The Anyplex™ II HPV28 assay detected more genotypes than the Cobas® HPV Test, but their clinical performances were similar.
高危型人乳头瘤病毒（HPV-HR）持续感染是宫颈癌的一个公认病因。本研究的目的是比较Cobas® HPV检测法和Anyplex™ II HPV28检测法在HPV检测和基因分型方面的分析性能和临床性能。共检测了94份宫颈样本。对于HPV-HR，两种检测结果的一致性非常好（94.68%），在检测CIN2+时一致性为100%。Anyplex™ II HPV28检测法比Cobas® HPV检测法检测出更多的基因型，但其临床性能相似。
