Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
J Ethnopharmacol. 2017 Apr 18;202:241-255. doi: 10.1016/j.jep.2017.03.022. Epub 2017 Mar 21.
Notopterygium incisum Ting ex H.T. Chang, known in Chinese as 'Qianghuo' is a traditional Chinese medicinal herb with the rhizome and roots associated with meridians of the kidney and urinary bladder. It is pungent, bitter and warm in nature. It has been used over the years to disperse cold, prevent painful obstructions from wind, damp and warm pain. It has also been used with other herbs to treat wind-cold exterior syndrome and wind-cold-damp bi-syndromes and has been known to grow well in regions of high altitude such as Gansu, Tibet etc.
This systematic review focuses on the ethnopharmacological uses of this herb, including recent advances on the phytochemical and pharmacological study of N. incisum. Recent analytical methods developed for the quantitative and qualitative determination of constituents in this herb have also been reviewed. Additionally, future trends and prospects in the study of this herb have been proposed.
Various literature and electronic databases such as Pubmed, Science Direct, Springer, Wiley etc were searched and data obtained. Other online academic libraries such as Google Scholar and ethnopharmacological literature were searched systematically for more information on the herb.
This review focuses on the ethnopharmacological uses of N. incisum and also the various chemical constituents present in the herb and their various therapeutic effects such as analgesic, anti-inflammatory, anti-cancer and antioxidants effects. Analytical methods developed for the quantitative and qualitative determination of various compounds in this herb were further reviewed.
In this paper, we have reviewed various researches conducted on N. incisum especially in areas of its ethnopharmacological use, phytochemicals, pharmacology and developed analytical methods. This herb has been used over the years in treating headache, rheumatoid arthritis, cold, diaphoretic etc, prompting many types of research into identifying which compounds are responsible for these activities and their mechanism of action. More research is needed in the area of pharmacokinetics and toxicology to give further information on the clinical use and control the quality of the herb.
羌活，又称“羌活”，是中国传统草药的一种，其根茎和根与肾和膀胱经有关。它的性质辛辣、苦、温。多年来，它一直被用于驱散寒冷，防止风寒湿温疼痛的阻塞。它也与其他草药一起用于治疗风寒表证和风寒湿痹证，并且在甘肃、西藏等高海拔地区生长良好。
本系统综述重点介绍了该草药的民族药理学用途，包括羌活植物化学和药理学研究的最新进展。还回顾了最近为定量和定性测定该草药中成分而开发的分析方法。此外，还提出了该草药研究的未来趋势和前景。
检索了各种文献和电子数据库，如 Pubmed、Science Direct、Springer、Wiley 等，并获取了数据。还通过 Google Scholar 和民族药理学文献等其他在线学术图书馆系统地搜索了更多关于该草药的信息。
本综述重点介绍了羌活的民族药理学用途，以及该草药中存在的各种化学成分及其各种治疗作用，如镇痛、抗炎、抗癌和抗氧化作用。还进一步回顾了为定量和定性测定该草药中各种化合物而开发的分析方法。
在本文中，我们综述了对羌活进行的各种研究，特别是在其民族药理学用途、植物化学、药理学和开发的分析方法方面的研究。多年来，该草药一直用于治疗头痛、类风湿性关节炎、感冒、发汗等疾病，促使人们进行了许多类型的研究，以确定哪些化合物负责这些活动及其作用机制。在药代动力学和毒理学领域需要更多的研究，以提供关于临床应用的进一步信息，并控制草药的质量。
