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托珠单抗成功治疗白塞氏葡萄膜炎。

Successful treatment of Behçet's uveitis with Tocilizumab.

作者信息

Alokaily F, Al Saati A, Jawad A

机构信息

Prince Sultan Military Medical City, Department of Medicine, Rheumatology Division, Department of Ophthalmology, Saudi Arabia.

出版信息

Saudi J Ophthalmol. 2017 Jan-Mar;31(1):42-44. doi: 10.1016/j.sjopt.2016.12.004. Epub 2016 Dec 20.

Abstract

A 33-year-old man with history of lymphoma was misdiagnosed as multiple sclerosis (MS) 18 months previously, developed intermediate uveitis, unresponsive to interferon, and corticosteroids. A diagnosis of Behçet's disease (BD) was made on the basis of recurrent orogenital ulceration, erythema nodosum, and a positive pathergy test. The patient was started on Tocilizumab and experienced an improvement in visual acuity and intraocular inflammation over the following 2 weeks. In patients with BD-related uveitis, Tocilizumab can be an effective alternative to anti-tumor necrosis factor alpha medications.

摘要

一名有淋巴瘤病史的33岁男性18个月前被误诊为多发性硬化症(MS),并发中间葡萄膜炎,对干扰素和皮质类固醇治疗无反应。根据复发性口生殖器溃疡、结节性红斑和针刺试验阳性,诊断为白塞病(BD)。患者开始使用托珠单抗治疗,在接下来的2周内视力和眼内炎症有所改善。对于与BD相关的葡萄膜炎患者,托珠单抗可作为抗肿瘤坏死因子α药物的有效替代药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b38/5352938/adc36b5586f3/gr1.jpg

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