嗜酸性肉芽肿性多血管炎（原称变应性肉芽肿性血管炎）作为高嗜酸性粒细胞综合征的鉴别诊断。
Eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) as a differential diagnosis of hypereosinophilic syndromes.
作者信息
Santos Yuri Albuquerque Pessoa, Silva Bruno Rangel Antunes, Lira Pollyanna Natividade Zanconato Barros Assis, Vaz Luiz Carlos Aguiar, Mafort Thiago Thomaz, Bruno Leonardo Palermo, Lopes Agnaldo José
机构信息
Department of Clinical Medicine, University Hospital Pedro Ernesto, State University of Rio de Janeiro, Boulevard 28 de Setembro, 77, 3º andar, Vila Isabel, 20551-030, Rio de Janeiro, Brazil.
Department of Pneumology, University Hospital Pedro Ernesto, State University of Rio de Janeiro, Boulevard 28 de Setembro, 77, 2º andar, Vila Isabel, 20551-030, Rio de Janeiro, Brazil; Postgraduate Programme in Medical Sciences, School of Medical Sciences, State University of Rio de Janeiro, Av. Prof. Manoel de Abreu, 444, 2º andar, Vila Isabel, 20550-170, Rio de Janeiro, Brazil.
出版信息
Respir Med Case Rep. 2017 Mar 8;21:1-6. doi: 10.1016/j.rmcr.2017.03.006. eCollection 2017.
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a rare systemic disease situated between primary small vessel vasculitides associated with antineutrophil cytoplasmic antibodies (ANCAs) and hypereosinophilic syndromes (HES). Here, we present a case of EGPA in a 38-year-old male, with a previous diagnosis of asthma, who presented with fever, migratory lung infiltrates and systemic eosinophilia that was refractory to previous courses of antibiotics. This case highlights the importance of the primary care physician understanding the differential diagnosis of pulmonary eosinophilic syndromes.
嗜酸性肉芽肿性多血管炎（EGPA），以前称为变应性肉芽肿性血管炎，是一种罕见的系统性疾病，介于与抗中性粒细胞胞浆抗体（ANCA）相关的原发性小血管血管炎和高嗜酸性粒细胞综合征（HES）之间。在此，我们报告一例38岁男性的EGPA病例，该患者既往诊断为哮喘，此次出现发热、游走性肺部浸润和全身嗜酸性粒细胞增多，对先前的抗生素治疗无效。该病例强调了初级保健医生了解肺部嗜酸性粒细胞综合征鉴别诊断的重要性。
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