Li Wei, Risacher Shannon L, McAllister Thomas W, Saykin Andrew J
Master of Physician Assistant Studies, School of Health & Rehabilitation Sciences, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Alzheimers Dement (Amst). 2017 Mar 2;6:196-200. doi: 10.1016/j.dadm.2017.01.008. eCollection 2017.
The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable.
Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old).
The cTBI group has a higher Everyday Cognition total score than the aTBI group. All perceived cognitive functions are worse for the cTBI group than for the aTBI group except memory. By contrast, the cTBI group has higher assessment scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than the aTBI group.
The AAI is associated with the long-term cognitive outcomes in older adults with a history of TBI.
受伤年龄（AAI）与创伤性脑损伤（TBI）的长期认知结果之间的关联存在争议。
来自阿尔茨海默病神经影像倡议组织的有TBI病史的合格参与者被分为儿童期TBI（cTBI）组（AAI≤21岁）和成人TBI（aTBI）组（AAI>21岁）。
cTBI组的日常认知总分高于aTBI组。除记忆外，cTBI组所有感知到的认知功能均比aTBI组差。相比之下，cTBI组在波士顿命名测试或雷伊听觉词语学习测试中的评估得分高于aTBI组。
AAI与有TBI病史的老年人的长期认知结果相关。
