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Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice.

作者信息

Nutt D J, Lister R G

机构信息

Laboratory of Clinical Studies, NIAAA, Bethesda, MD.

出版信息

Psychopharmacology (Berl). 1988;94(3):335-6. doi: 10.1007/BF00174705.

DOI:10.1007/BF00174705
PMID:2833761
Abstract
摘要

相似文献

1
Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice.小鼠对苯二氮䓬受体反向激动剂（FG 7142）反应的品系差异。
Psychopharmacology (Berl). 1988;94(3):335-6. doi: 10.1007/BF00174705.
2
Are changes in glutamatergic mechanisms responsible for kindling to the benzodiazepine receptor inverse agonist, FG 7142?
Br J Pharmacol. 1989 Dec;98 Suppl:837P.
3
Inverse agonist properties of the FG 7142 discriminative stimulus.
Pharmacol Biochem Behav. 1991 Jan;38(1):99-104. doi: 10.1016/0091-3057(91)90595-s.
4
Benzodiazepine inverse agonist FG-7142-induced delayed behavioral depression in mice.苯二氮䓬反向激动剂FG-7142诱导小鼠出现延迟性行为抑郁。
Arch Int Pharmacodyn Ther. 1988 Jul-Aug;294:56-63.
5
Increased sensitivity to inverse agonists and decreased GABA-stimulated chloride influx induced by chronic treatment with FG 7142.
Adv Biochem Psychopharmacol. 1988;45:293-306.
6
Suppression of the immune response by benzodiazepine receptor inverse agonists.苯二氮䓬受体反向激动剂对免疫反应的抑制作用。
J Neuroimmunol. 1987 May;15(1):1-9. doi: 10.1016/0165-5728(87)90002-6.
7
Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice.小鼠对苯二氮䓬受体配体低温效应敏感性的品系差异。
Psychopharmacology (Berl). 1992;109(3):365-8. doi: 10.1007/BF02245884.
8
Bi-directional changes in sham feeding in the rat produced by benzodiazepine receptor ligands.
Physiol Behav. 1988;42(3):211-6. doi: 10.1016/0031-9384(88)90072-8.
9
Chronic benzodiazepine administration. VIII. Receptor upregulation produced by chronic exposure to the inverse agonist FG-7142.长期使用苯二氮䓬类药物。VIII. 长期暴露于反向激动剂FG - 7142所产生的受体上调。
J Pharmacol Exp Ther. 1991 Jul 1;258(1):280-5.
10
Augmentation of GABAA receptor function by chronic exposure to GABA-neutral and GABA-negative benzodiazepine ligands in cultured cortical neurons.在培养的皮质神经元中，长期暴露于GABA中性和GABA阴性苯二氮䓬配体可增强GABAA受体功能。
Biochem Pharmacol. 1990 Sep 15;40(6):1337-44. doi: 10.1016/0006-2952(90)90401-6.

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Studying autism in rodent models: reconciling endophenotypes with comorbidities.研究啮齿动物模型中的自闭症：协调表型与共病。
Front Hum Neurosci. 2013 Jul 25;7:417. doi: 10.3389/fnhum.2013.00417. eCollection 2013.
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Measuring anxiety- and locomotion-related behaviours in mice: a new way of using old tests.测量小鼠的焦虑和运动行为：旧测试的新用途。
Psychopharmacology (Berl). 2010 Jul;211(1):99-112. doi: 10.1007/s00213-010-1873-0. Epub 2010 May 8.
3
Pharmacology of the beta-carboline FG-7,142, a partial inverse agonist at the benzodiazepine allosteric site of the GABA A receptor: neurochemical, neurophysiological, and behavioral effects.

本文引用的文献

1
Strain differences in susceptibility to the convulsant actions of 3-carbomethoxy-beta-carboline.对3-甲氧羰基-β-咔啉惊厥作用易感性的品系差异
Pharmacol Biochem Behav. 1983 Dec;19(6):951-5. doi: 10.1016/0091-3057(83)90397-0.
2
Interaction of convulsive ligands with benzodiazepine receptors.惊厥性配体与苯二氮䓬受体的相互作用。
Science. 1982 Jun 11;216(4551):1241-3. doi: 10.1126/science.6281892.
3
Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats.β-咔啉羧酸乙酯降低大鼠的癫痫发作阈值，并拮抗氟西泮诱导的镇静作用。
β-咔啉FG-7142的药理学研究，它是GABAA受体苯二氮䓬变构位点的部分反向激动剂：神经化学、神经生理学及行为学效应
CNS Drug Rev. 2007 Winter;13(4):475-501. doi: 10.1111/j.1527-3458.2007.00025.x.
4
A mouse mutant strain highly resistant to methyl beta-carboline-3-carboxylate-induced seizures.一种对β-咔啉-3-羧酸甲酯诱导的癫痫发作具有高度抗性的小鼠突变品系。
Exp Brain Res. 1996 Jun;110(1):28-35. doi: 10.1007/BF00241371.
5
Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains.AXB和BXA重组近交系小鼠焦虑相关行为及对苯二氮䓬类药物反应的遗传分析。
Behav Genet. 1995 Nov;25(6):557-68. doi: 10.1007/BF02327579.
6
Characterization of benzodiazepine-sensitive behaviors in the A/J and C57BL/6J inbred strains of mice.A/J和C57BL/6J近交系小鼠中苯二氮䓬敏感性行为的特征分析。
Behav Genet. 1994 Mar;24(2):171-80. doi: 10.1007/BF01067821.
7
Evidence for a multigenic system controlling methyl-beta-carboline-3-carboxylate (beta-CCM)-induced seizures.一个控制甲基-β-咔啉-3-羧酸盐（β-CCM）诱发癫痫的多基因系统的证据。
Behav Genet. 1994 May;24(3):285-97. doi: 10.1007/BF01067195.
8
A review of evidence for GABergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: more support for a continuum hypothesis of "functional" psychosis.关于γ-氨基丁酸能占优势/谷氨酸能缺陷作为精神分裂症和情感性精神病共同病因因素的证据综述：对“功能性”精神病连续体假说的更多支持
Neurochem Res. 1991 Oct;16(10):1099-111. doi: 10.1007/BF00966587.
9
Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice.小鼠对苯二氮䓬受体配体低温效应敏感性的品系差异。
Psychopharmacology (Berl). 1992;109(3):365-8. doi: 10.1007/BF02245884.
Nature. 1981 Mar 5;290(5801):54-5. doi: 10.1038/290054a0.
4
Differential pharmacological effects of benzodiazepine receptor inverse agonists.
Adv Biochem Psychopharmacol. 1983;38:57-64.
5
Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling.苯二氮䓬受体配体FG 7142的急性和慢性效应：惊厥特性与点燃效应
Br J Pharmacol. 1984 Dec;83(4):951-8. doi: 10.1111/j.1476-5381.1984.tb16536.x.
6
Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptor occupancy.地西泮在不同小鼠品系中的长效抗惊厥作用：与脑内浓度及受体占有率的相关性
Psychopharmacology (Berl). 1985;86(1-2):137-41. doi: 10.1007/BF00431698.
7
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.针对乙醇戒断严重程度进行选择性培育的小鼠品系中抗惊厥敏感性的基因差异。
J Pharmacol Exp Ther. 1986 Oct;239(1):154-9.
8
Mouse lines selected for genetic differences in diazepam sensitivity.因地西泮敏感性存在遗传差异而被挑选出的小鼠品系。
Psychopharmacology (Berl). 1987;93(1):25-30. doi: 10.1007/BF02439582.