Coyle Meaghan E, Liang Haiying, Wang Kaiyi, Zhang Anthony Lin, Guo Xinfeng, Lu Chuanjian, Xue Charlie C
China-Australia International Research Centre for Chinese Medicine & School of Health and Biomedical Sciences, RMIT University, Bundoora Campus, Melbourne, VIC, 3083, Australia.
Guangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, and The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Dermatol Ther. 2017 Jul;30(4). doi: 10.1111/dth.12468. Epub 2017 Mar 24.
Herpes zoster is an acute inflammatory condition which can have a significant impact on quality of life. Antiviral therapies are effective, but do not meet patients' expectations of symptomatic relief. Acupuncture and moxibustion have been used for herpes zoster; this systematic review evaluated their efficacy and safety. Nine English and Chinese databases were searched from their inceptions to March 2016. Randomized controlled trials evaluating the combination of acupuncture plus moxibustion in adult herpes zoster were included. Outcomes included pain intensity and duration, quality of life and adverse events. Meta-analysis was performed using RevMan software (version 5.3). Nine studies (945 participants) were included. Studies were of low to moderate methodological quality based on risk of bias assessment. Pain intensity (visual analogue scale) was lower among those who received acupuncture plus moxibustion compared with pharmacotherapy (one study; MD -8.25 mm, 95% CI -12.36 to -4.14). The clinical significance of this result is yet to be established. Some benefits were seen for other pain and cutaneous outcomes, and global improvement in symptoms. Mild adverse events were reported in the intervention groups. Acupuncture plus moxibustion may improve pain and cutaneous outcomes, although current evidence is limited by the number of studies and methodological shortcomings.
带状疱疹是一种急性炎症性疾病，会对生活质量产生重大影响。抗病毒疗法有效，但未达到患者对症状缓解的期望。针灸已用于治疗带状疱疹；本系统评价评估了其疗效和安全性。检索了9个英文和中文数据库，检索时间从建库至2016年3月。纳入了评估针灸联合艾灸治疗成人带状疱疹的随机对照试验。结局指标包括疼痛强度和持续时间、生活质量和不良事件。使用RevMan软件（5.3版）进行荟萃分析。纳入了9项研究（945名参与者）。根据偏倚风险评估，研究的方法学质量为低到中等。与药物治疗相比，接受针灸联合艾灸的患者疼痛强度（视觉模拟量表）更低（1项研究；MD -8.25 mm，95%CI -12.36至-4.14）。该结果的临床意义尚待确定。在其他疼痛和皮肤结局以及症状总体改善方面观察到了一些益处。干预组报告了轻度不良事件。针灸联合艾灸可能改善疼痛和皮肤结局，尽管目前的证据受到研究数量和方法学缺陷的限制。
