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针刺相关疗法治疗带状疱疹疗效的比较：一项随机对照试验的网络荟萃分析。

Comparison of efficacy of acupuncture-related therapy in the treatment of herpes zoster: A network meta-analysis of randomized controlled trials.

机构信息

Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.

Shapingba Hospital, Chongqing University, Chongqing, China.

出版信息

Medicine (Baltimore). 2023 Sep 29;102(39):e34920. doi: 10.1097/MD.0000000000034920.

DOI:10.1097/MD.0000000000034920
PMID:37773829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10545332/
Abstract

OBJECTIVE

A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted to evaluate the efficacy and safety of acupuncture-related therapy in the treatment of herpes zoster (HZ) and to provide a reference for the clinical treatment of herpes zoster.

METHODS

PubMed, Cochrane Library, EMBASE, Web of Science, CNKI, VIP database, Wanfang Database, and SinoMED Chinese and English databases were systematically searched for RCTs on acupuncture-related therapy for HZ until February 2023. Literature screening, data extraction, and risk of bias assessment were performed independently by 2 researchers. R4.2.1 and Stata15.1 software were used for data analysis.

RESULTS

A total of 26 RCTs involving 1929 HZ patients were included, and the network meta-analysis results showed that acupotomy appeared to be most effective in terms of improving VAS scores and the time of incrustation; SUCRA cumulative probability ranking showed the best efficacy of bloodletting in improving efficiency and the time of ceasing new blisters, acupuncture in improving the time of decrustation, and moxibustion in reducing the incidence of postherpetic neuralgia (PHN).

CONCLUSIONS

Through a comprehensive comparison of 9 different acupuncture therapies, acupotomy was the optimal treatment to improve VAS pain scores and the time of incrustation; bloodletting, acupuncture, fire needle, and moxibustion could be effective intervention measures to improve the time of ceasing new blisters and decrustation and reduce the incidence of PHN; Western medicine was closely related to adverse reactions. The conclusions need to be further verified due to the limitations of the study.

摘要

目的

系统评价和荟萃分析随机对照试验（RCT），以评估针灸相关疗法治疗带状疱疹（HZ）的疗效和安全性，为带状疱疹的临床治疗提供参考。

方法

系统检索 PubMed、Cochrane 图书馆、EMBASE、Web of Science、中国知网、维普数据库、万方数据库、中国生物医学文献服务系统（SinoMed）中英文数据库，收集针灸相关疗法治疗带状疱疹的 RCT，检索时限均从建库至 2023 年 2 月。由 2 位研究者独立进行文献筛选、数据提取和偏倚风险评估，采用 R4.2.1 和 Stata15.1 软件进行数据分析。

结果

共纳入 26 项 RCT，包含 1929 例带状疱疹患者。网络荟萃分析结果显示，针刀松解术在改善 VAS 评分和结痂时间方面可能效果最佳；SUCRA 累积概率排序显示，刺络拔罐在提高有效率和停止新发水疱时间方面疗效最佳，针刺在改善脱痂时间方面疗效最佳，艾灸在降低带状疱疹后神经痛（PHN）发生率方面疗效最佳。

结论

通过对 9 种不同针灸疗法的全面比较，针刀松解术是改善 VAS 疼痛评分和结痂时间的最佳治疗方法；刺络拔罐、针刺、火针、艾灸可能是改善停止新发水疱和脱痂时间、降低 PHN 发生率的有效干预措施；西药与不良反应密切相关。由于研究的局限性，需要进一步验证这些结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/e3a373c229b2/medi-102-e34920-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/314b0e95dcb2/medi-102-e34920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/d97ad5a89ddd/medi-102-e34920-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/2914d939f53f/medi-102-e34920-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/38cbd66c5130/medi-102-e34920-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/e86342ac0437/medi-102-e34920-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/f33932088ebb/medi-102-e34920-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/3e04c753fefa/medi-102-e34920-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/406726bada85/medi-102-e34920-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/ea29bf3f485a/medi-102-e34920-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/e3a373c229b2/medi-102-e34920-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/314b0e95dcb2/medi-102-e34920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/d97ad5a89ddd/medi-102-e34920-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/2914d939f53f/medi-102-e34920-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/38cbd66c5130/medi-102-e34920-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/e86342ac0437/medi-102-e34920-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/f33932088ebb/medi-102-e34920-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/3e04c753fefa/medi-102-e34920-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/406726bada85/medi-102-e34920-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/ea29bf3f485a/medi-102-e34920-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6156/10545332/e3a373c229b2/medi-102-e34920-g010.jpg

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