Takai Keisuke, Komori Takashi, Niimura Manabu, Taniguchi Makoto
Departments of 1 Neurosurgery, and.
Laboratory Medicine and Pathology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.
J Neurosurg Spine. 2017 Jun;26(6):751-753. doi: 10.3171/2016.11.SPINE16488. Epub 2017 Mar 24.
In most patients with superficial siderosis of the CNS, the exact source of bleeding remains unknown because of a lack of objective surgical data. The authors herein describe the case of a 58-year-old man with superficial siderosis of the CNS. The patient also had spinal CSF leakage due to a spinal dural defect. Repair surgery for the dural defect was performed using posterior laminoplasty with a transdural approach without spinal fixation. During repair surgery, the bleeding source was found to be the epidural vein around the defect. The intraoperative and histological results of the present case suggest that epidural veins exposed to CSF represent a chronic bleeding source in patients with superficial siderosis of the CNS complicated by CSF leakage. Dural repair surgery may result in discontinuation of the CSF leaks, resolution of the epidural CSF collection, and cessation of chronic epidural bleeding.
在大多数中枢神经系统浅表性铁沉积症患者中,由于缺乏客观的手术数据,出血的确切来源尚不清楚。本文作者描述了一名58岁中枢神经系统浅表性铁沉积症男性患者的病例。该患者还因硬脊膜缺损出现脊髓脑脊液漏。采用经硬脊膜入路的后路椎板成形术且不进行脊柱固定,对硬脊膜缺损进行修复手术。在修复手术过程中,发现出血源为缺损周围的硬膜外静脉。本病例的术中及组织学结果表明,暴露于脑脊液的硬膜外静脉是中枢神经系统浅表性铁沉积症合并脑脊液漏患者的慢性出血源。硬脊膜修复手术可能导致脑脊液漏停止、硬膜外脑脊液积聚消退以及慢性硬膜外出血停止。