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Cohort Profile: Scottish Diabetes Research Network Type 1 Bioresource Study (SDRNT1BIO).

作者信息

Akbar Tahira, McGurnaghan Stuart, Palmer Colin N A, Livingstone Shona J, Petrie John, Chalmers John, Lindsay Robert S, McKnight John A, Pearson Donald W M, Patrick Alan W, Walker James, Looker Helen C, Colhoun Helen M

机构信息

Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.

Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, UK.

出版信息

Int J Epidemiol. 2017 Jun 1;46(3):796-796i. doi: 10.1093/ije/dyw152.

DOI:10.1093/ije/dyw152
PMID:28338705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5582633/
Abstract
摘要

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mutation alters immune system activation, inflammation, and risk of autoimmunity.突变改变免疫系统的激活、炎症和自身免疫的风险。
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J Diabetes Complications. 2021 Apr;35(4):107842. doi: 10.1016/j.jdiacomp.2020.107842. Epub 2021 Jan 9.
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Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.免疫球蛋白 G 的糖基化受与炎症性疾病多效性相关的庞大基因网络调控。
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本文引用的文献

1
Insulin pump therapy, multiple daily injections, and cardiovascular mortality in 18,168 people with type 1 diabetes: observational study.胰岛素泵治疗、多次每日注射与 18168 例 1 型糖尿病患者的心血管死亡率:观察性研究。
BMJ. 2015 Jun 22;350:h3234. doi: 10.1136/bmj.h3234.
2
The genetics of diabetic complications.糖尿病并发症的遗传学。
Nat Rev Nephrol. 2015 May;11(5):277-87. doi: 10.1038/nrneph.2015.37. Epub 2015 Mar 31.
3
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.1型糖尿病易感基因座的精细定位以及因果变异与淋巴样基因增强子共定位的证据。
Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.
4
Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010.2008 - 2010年苏格兰1型糖尿病队列的预期寿命估计
JAMA. 2015 Jan 6;313(1):37-44. doi: 10.1001/jama.2014.16425.
5
SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.SORBS1基因,糖尿病肾病的一个新候选基因:1型糖尿病患者多阶段全基因组关联研究结果
Diabetologia. 2015 Mar;58(3):543-8. doi: 10.1007/s00125-014-3459-6. Epub 2014 Dec 6.
6
A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain.一项全基因组关联研究表明,8号染色体短臂21.3区(GFRA2)与糖尿病性神经病理性疼痛存在关联。
Eur J Pain. 2015 Mar;19(3):392-9. doi: 10.1002/ejp.560.
7
Update on cardiovascular outcomes at 30 years of the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.糖尿病控制与并发症试验/糖尿病干预与并发症流行病学研究30年心血管结局最新情况
Diabetes Care. 2014;37(1):39-43. doi: 10.2337/dc13-2116.
8
The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells.大多数长病程 1 型糖尿病患者都是胰岛素微量分泌者,且β细胞仍具有功能。
Diabetologia. 2014 Jan;57(1):187-91. doi: 10.1007/s00125-013-3067-x.
9
Improved genetic testing for monogenic diabetes using targeted next-generation sequencing.使用靶向下一代测序技术改善单基因糖尿病的基因检测。
Diabetologia. 2013 Sep;56(9):1958-63. doi: 10.1007/s00125-013-2962-5. Epub 2013 Jun 15.
10
Genetics of diabetes--are we missing the genes or the disease?糖尿病遗传学——我们是遗漏了基因还是疾病?
Mol Cell Endocrinol. 2014 Jan 25;382(1):726-739. doi: 10.1016/j.mce.2013.04.002. Epub 2013 Apr 13.