大型噬菌体中的对称性错配与DNA包装
Symmetry mismatch and DNA packaging in large bacteriophages.
作者信息
Hendrix R W
出版信息
Proc Natl Acad Sci U S A. 1978 Oct;75(10):4779-83. doi: 10.1073/pnas.75.10.4779.
Abstract
A model is presented for the mechanism of packaging double-stranded DNA into phage heads. The model is based on, and rationalizes, the mismatch in symmetry between the heads and tails of large bacteriophages. DNA movement is postulated to be mediated by a rotating protein structure at the tail-proximal vertex of the head.
摘要
提出了一种将双链DNA包装到噬菌体头部的机制模型。该模型基于大型噬菌体头部与尾部对称性的不匹配，并对其进行了合理说明。推测DNA的移动是由头部尾部近端顶点处的旋转蛋白结构介导的。
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