Clinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, London, UK.
Emergency Department, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, London, UK.
QJM. 2017 Oct 1;110(10):619-622. doi: 10.1093/qjmed/hcx045.
In May 2016, the UK Government enacted the Psychoactive Substances Act which made it an offense to produce or supply many drugs including new psychoactive substances (NPS).
We aimed to assess the impact of the Act on the availability of the synthetic cannabinoid receptor agonist methyl 2-[[1-(cyclohexylmethyl)indole-3-carbonyl]amino]-3,3-dimethylbutanoate (MDMB-CHMICA) from internet-based suppliers.
Internet snapshot availability study.
We conducted two snapshot availability surveys looking at the number of websites offering to sell MDMB-CHMICA: the first in March prior to implementation of the Act and the second in June, 1 month post-implementation.
In March and June 2016, we identified 47 and 38 websites, respectively, which offered to sell MDMB-CHMICA. There were no significant differences in the price of the drug nor the forms available for purchase. In the June survey there was a significant decrease in the number of websites which openly stated they were based in the UK (from 14 down to 2), three websites stated that they did not supply customers based in the UK and two websites stated they had ceased sales of MDMB-CHMICA due to the Act.
This study showed a small but limited reduction in the availability of MDMB-CHMICA from internet-based suppliers following implementation of the Act.
2016 年 5 月，英国政府颁布了《精神药物法》，规定制造或供应许多药物，包括新的精神活性物质（NPS），属于违法行为。
我们旨在评估该法案对互联网供应商供应合成大麻素受体激动剂甲基 2-[[1-(环己基甲基)吲哚-3-羰基]氨基]-3,3-二甲基丁酸酯（MDMB-CHMICA）的影响。
基于互联网的快照可用性研究。
我们进行了两次快照可用性调查，调查了提供销售 MDMB-CHMICA 的网站数量：第一次是在该法案实施前的 2016 年 3 月，第二次是在实施后的 2016 年 6 月。
在 2016 年 3 月和 6 月，我们分别确定了 47 家和 38 家网站提供销售 MDMB-CHMICA。药品的价格和可供购买的形式没有显著差异。在 6 月的调查中，明确表示他们位于英国的网站数量从 14 家显著减少到 2 家，有 3 家网站表示他们不向英国客户供应，有 2 家网站表示由于该法案已停止销售 MDMB-CHMICA。
本研究表明，该法案实施后，互联网供应商供应 MDMB-CHMICA 的数量略有减少，但有限。
