The Effects of Positive End-Expiratory Pressure at Different Levels on Postoperative Respiration Parameters in Patients Undergoing Laparoscopic Cholecystectomy.

UNLABELLED

Purpose/Aim of the study: We investigated the effects of different positive end-expiratory pressure (PEEP) levels on postoperative respiration parameters in patients undergoing laparoscopic cholecystectomy.

MATERIALS AND METHODS

One hundred and five consecutive patients were randomly divided to three groups (n = 35, for each group). Group I did not receive PEEP whereas group II received PEEP as 5 cmHO and group III received PEEP as 8 cm HO. Measurements with spirometer were taken 1 hour before the operation (T) and, 1 (T), 6 (T), and 24 hours (T) after extubation by an anesthetist. Forced expiratory volume (FEV), forced vital capacity (FVC), and peak expiratory flow (PEF) were recorded.

RESULTS

Group I had higher FVC values measured at T time point compared with other groups (p < 0.05, for both groups). There was a statistically significant difference between group I and group III in terms of the FVC values measured at T and T time points (p = 0.05 and p < 0.05, retrospectively). A statistical difference was found between group I and group II in terms of FEV measured at T time point (p < 0.05). Group I had higher FEV values measured at T and T time points compared to group III (p = 0.05, P<0.05; respectively). Group III had lower PEF values measured at T time point compared to group I and II (p < 0.05).

CONCLUSIONS

We concluded that PEEP with 5 or 8 cmHO has negative effects on lung function tests measured with spirometer during postoperative 1, 6, and 24 hours in patients underwent elective laparoscopic cholecystectomy.