Zheng J, Li Z, Li Q, Li X
Cardiac Surgery Department, Beijing Children's Hospital affiliated to Capital Medical University, 56 Nan Lishi Road, Xi Cheng District, 100045, Beijing, China.
Herz. 2018 May;43(3):238-245. doi: 10.1007/s00059-017-4553-6. Epub 2017 Mar 24.
This meta-analysis was designed to determine the effect of an intracardiac lateral tunnel (ILT) versus an extracardiac conduit (ECC) on patients undergoing a Fontan procedure. A search of the literature in PubMed, Embase, China Academic Literature, and Wanfang databases yielded 23 studies comprising approximately 1000 patients for analysis. There were statistically significant differences between ILT and ECC in the frequency of early sinus node dysfunction, early total arrhythmias, late supraventricular tachycardia, late sinus node dysfunction, late total arrhythmias, and need for pacemaker. By contrast, no statistically significant differences between the two methods were found in takedown, protein-losing enteropathy, thromboembolic events, early supraventricular tachycardia, early mortality, and total mortality. We conclude that an ECC confers some advantages over an ILT, although the underlying mechanism remains unclear.
本荟萃分析旨在确定心内隧道（ILT）与心外管道（ECC）对接受Fontan手术患者的影响。检索PubMed、Embase、中国学术文献和万方数据库中的文献，得到23项研究，共约1000例患者纳入分析。ILT与ECC在早期窦房结功能障碍、早期总心律失常、晚期室上性心动过速、晚期窦房结功能障碍、晚期总心律失常以及起搏器需求频率方面存在统计学显著差异。相比之下，两种方法在拆除手术、蛋白丢失性肠病、血栓栓塞事件、早期室上性心动过速、早期死亡率和总死亡率方面未发现统计学显著差异。我们得出结论，ECC相对于ILT具有一些优势，尽管其潜在机制尚不清楚。
