Effect of NCO-700, an inhibitor of thiol protease, on reactive oxygen production by chemotactic peptide-stimulated rabbit peripheral granulocytes.
作者信息
Tawara K, Fujisawa S, Nakai K
机构信息
Department of Pharmacology, Akita University School of Medicine, Japan.
出版信息
Experientia. 1988 Apr 15;44(4):346-7. doi: 10.1007/BF01961277.
PMID:2834217
Abstract
The specific thiol protease inhibitor, NCO-700, which is related to L-trans-epoxysuccinylpeptides, inhibited oxidant production by chemoattractant-stimulated rabbit polymorphonuclear leukocytes. NCO-700 could also scavenge active oxygen generated from sodium hypochlorite-hydrogen peroxide and hypoxanthine-xanthine oxidase systems.
摘要
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