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研究 10.5 特斯拉静磁场暴露对麻醉猪的生理影响。

Investigating the physiological effects of 10.5 Tesla static field exposure on anesthetized swine.

机构信息

Center for Magnetic Resonance Research (CMRR) at University of Minnesota, Minneapolis, Minnesota, USA.

Dermatology Service, Memorial Sloan Kettering Cancer Center, Minneapolis, Minnesota, USA.

出版信息

Magn Reson Med. 2018 Jan;79(1):511-514. doi: 10.1002/mrm.26672. Epub 2017 Mar 25.

DOI:10.1002/mrm.26672
PMID:28342176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5612859/
Abstract

PURPOSE

In this work, we investigated the relative effects of static magnetic field exposure (10.5 Tesla [T]) on two physiological parameters; blood pressure (BP) and heart rate (HR).

METHODS

In vivo, we recorded both BP and HR in 4 swine (3 female, 1 male) while they were positioned within a 10.5T magnet. All measurements were performed invasively within these anesthetized animals by the placement of pressure catheters into their carotid arteries.

RESULTS

We measured average increases of 2.0 mm Hg (standard deviation [SD], 6.9) in systolic BP and an increase of 4.5 mm Hg (SD, 13.7) in the diastolic BPs: We also noted an average increase of 1.2 beats per minute (SD, 2.5) in the HRs during such.

CONCLUSION

Data regarding changes in BP and HR in anesthetized swine attributed to whole-body 10.5T exposure are reported. Magn Reson Med 79:511-514, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

摘要

目的

在这项工作中，我们研究了静磁场暴露（10.5T）对两种生理参数（血压[BP]和心率[HR]）的相对影响。

方法

在体内，我们在 4 头猪（3 头雌性，1 头雄性）内记录了他们在 10.5T 磁体内的 BP 和 HR。所有测量都是通过将压力导管插入颈动脉来在这些麻醉动物体内进行的。

结果

我们测量到收缩压平均升高 2.0mmHg（标准差[SD]，6.9），舒张压升高 4.5mmHg（SD，13.7）：我们还注意到 HR 平均增加 1.2 次/分钟（SD，2.5）。

结论

报告了全身 10.5T 暴露导致麻醉猪的 BP 和 HR 变化的数据。磁共振医学 79:511-514，2018. © 2017 国际磁共振医学学会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/f83336c3fcac/nihms853950f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/f7d8f4debe47/nihms853950f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/63ee83d762ce/nihms853950f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/8fc936987ade/nihms853950f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/f83336c3fcac/nihms853950f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/f7d8f4debe47/nihms853950f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/63ee83d762ce/nihms853950f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/8fc936987ade/nihms853950f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5bd/5612859/f83336c3fcac/nihms853950f4.jpg

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