Chakeres Donald W, Kangarlu Alayar, Boudoulas Harisios, Young Donn C
Department of Radiology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA.
J Magn Reson Imaging. 2003 Sep;18(3):346-52. doi: 10.1002/jmri.10367.
To determine if increasing static magnetic field strength exposures up to 8 Tesla (T) affect vital signs or electrocardiograms (ECGs) in normal human volunteers.
We studied 25 normal subjects, consisting of 19 men and six women, ages 24-53 years. The vital signs and ECGs of the subjects were measured 14 times inside and outside the magnetic field. This included the heart rate, respiratory rate, systolic and diastolic blood pressures, finger pulse oxygenation levels, core body temperature via the external auditory canal temperature, and fiber optic core body sublingual temperatures. Inside the magnetic field the vital signs were measured sequentially at field strengths of 8, 6, 4.5, 3, and 1.5 T.
The only statistically significant effect of magnetic field strength was observed with systolic blood pressure. An average increase of 3.6 mm Hg in systolic blood pressure was seen with 8 T exposure. ECG rhythm strip analysis demonstrated no significant changes post-exposure.
Normal subjects exposed to varying magnetic field strengths of up to 8 T demonstrated no clinically significant changes in vital signs. Transient ECG artifacts were noted to increase with the field strength.
确定高达8特斯拉（T）的静态磁场强度暴露增加是否会影响正常人类志愿者的生命体征或心电图（ECG）。
我们研究了25名正常受试者，其中包括19名男性和6名女性，年龄在24至53岁之间。在磁场内外对受试者的生命体征和心电图进行了14次测量。这包括心率、呼吸频率、收缩压和舒张压、手指脉搏氧合水平、通过外耳道温度测量的核心体温以及光纤核心体温舌下温度。在磁场内，在8、6、4.5、3和1.5 T的场强下依次测量生命体征。
仅在收缩压方面观察到磁场强度具有统计学意义的唯一影响。在8 T暴露下，收缩压平均升高3.6毫米汞柱。心电图节律条分析显示暴露后无显著变化。
暴露于高达8 T的不同磁场强度下的正常受试者生命体征未出现临床显著变化。注意到短暂的心电图伪像随场强增加而增加。
