Machado-Moreira Christiano A, Taylor Nigel A S
Centre for Human and Applied Physiology, School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia.
Centre for Human and Applied Physiology, School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia.
J Therm Biol. 2017 Apr;65:145-152. doi: 10.1016/j.jtherbio.2017.03.002. Epub 2017 Mar 9.
Human eccrine sweat-gland recruitment and secretion rates were investigated from the glabrous (volar) and non-glabrous hand surfaces during psychogenic (mental arithmetic) and thermogenic stimuli (mild hyperthermia). It was hypothesised that these treatments would activate glands from both skin surfaces, with the non-thermal stimulus increasing secretion rates primarily by recruiting more sweat glands. Ten healthy men participated in two seated, resting trials in temperate conditions (25-26°C). Trials commenced under normothermic conditions during which the first psychogenic stress was applied. That was followed by passive heating (0.5°C mean body temperature elevation) and thermal clamping, with a second cognitive challenge then applied. Sudomotor activity was evaluated from both hands, with colourimetry used to identify activated sweat glands, skin conductance to determine the onset of precursor sweating and ventilated sweat capsules to measure rates of discharged sweating. From glandular activation and sweat rate data, sweat-gland outputs were derived. These psychogenic and thermogenic stimuli activated sweat glands from both the glabrous and non-glabrous skin surfaces, with the former dominating at the glabrous skin and the latter at the non-glabrous surface. Indeed, those stimuli individually accounted for ~90% of the site-specific maximal number of activated sweat glands observed when both stimuli were simultaneously applied. During the normothermic psychological stimulation, sweating from the glabrous surface was elevated via a 185% increase in the number of activated glands within the first 60s. The hypothetical mechanism for this response may involve the serial activation of additional eccrine sweat glands during the progressive evolution of psychogenic sweating.
在精神源性刺激（心算）和热源性刺激（轻度体温过高）期间，对无毛（手掌）和有毛手部皮肤表面的人类外泌汗腺募集和分泌率进行了研究。研究假设这些刺激会激活两个皮肤表面的腺体，非热刺激主要通过募集更多汗腺来提高分泌率。十名健康男性在温带条件（25 - 26°C）下参与了两项坐姿休息试验。试验在常温条件下开始，在此期间施加了第一次精神源性应激。随后是被动加热（平均体温升高0.5°C）和热钳制，然后施加第二次认知挑战。对双手的发汗运动活性进行评估，用比色法识别激活的汗腺，用皮肤电导率确定前驱出汗的开始，并使用通风汗液收集囊测量排汗率。根据腺体激活和出汗率数据得出汗腺输出量。这些精神源性和热源性刺激激活了无毛和有毛皮肤表面的汗腺，前者在无毛皮肤中占主导，后者在有毛皮肤表面占主导。事实上，当同时施加这两种刺激时，这些刺激各自约占观察到的特定部位激活汗腺最大数量的90%。在常温心理刺激期间，无毛表面的出汗在前60秒内通过激活腺体数量增加185%而升高。这种反应的假设机制可能涉及在精神源性出汗的渐进演变过程中额外外泌汗腺的系列激活。
