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采用保留拇指重建术治疗蕈样肉芽肿的手术切除

Surgical Excision of Mycosis Fungoides Using Thumb-Sparing Reconstruction.

作者信息

McEvenue Giancarlo, Kim Ashley, Binhammer Paul

机构信息

University of Toronto, Ontario, Canada.

University of Toronto, Ontario, Canada; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

出版信息

Hand (N Y). 2017 Mar;12(2):NP22-NP26. doi: 10.1177/1558944716669085. Epub 2016 Sep 23.

DOI:10.1177/1558944716669085
PMID:28344538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5349418/
Abstract

The differential for soft tissue tumors of the hand and upper limb is broad. Hematologic malignancy remains quite low on the differential for soft tissue tumors involving the hand, and there is little in the literature describing surgical management of such cutaneous manifestations. When the tumor is large or involves the thumb, careful consideration of reconstructive options is required. We present a rare case of an aggressively enlarging mycosis fungoides, a cutaneous T-cell lymphoma tumor, involving the thumb. This tumor had a history of multiple failed treatment attempts, including radiation and chemotherapy. Our surgical plan was a reverse radial forearm osteocutaneous flap. A reverse radial osteocutaneous forearm flap was successfully used to avoid thumb amputation and preserve thumb function.

摘要

手部和上肢软组织肿瘤的鉴别诊断范围很广。血液系统恶性肿瘤在手部软组织肿瘤的鉴别诊断中所占比例仍然很低,而且文献中很少描述此类皮肤表现的手术治疗方法。当肿瘤较大或累及拇指时,需要仔细考虑重建方案。我们报告了一例罕见的侵袭性增大的蕈样肉芽肿,这是一种累及拇指的皮肤T细胞淋巴瘤肿瘤。该肿瘤有多次治疗失败的病史,包括放疗和化疗。我们的手术方案是采用桡骨前臂逆行骨皮瓣。桡骨前臂逆行骨皮瓣成功用于避免拇指截肢并保留拇指功能。

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引用本文的文献

1
The Role of Surgery to Relieve Symptomatic Cutaneous T-Cell Lymphoma Refractory to Medical Treatments.手术在缓解对药物治疗难治的有症状皮肤T细胞淋巴瘤中的作用。
Case Rep Oncol Med. 2024 Apr 26;2024:6645278. doi: 10.1155/2024/6645278. eCollection 2024.

本文引用的文献

1
Primary cutaneous B-cell lymphoma: Role of surgery.原发性皮肤B细胞淋巴瘤:手术的作用
Can J Plast Surg. 2011 Summer;19(2):e12-4.
2
Survival outcomes and prognostic factors in mycosis fungoides/Sézary syndrome: validation of the revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer staging proposal.蕈样肉芽肿/赛泽里综合征的生存结局和预后因素:修订的国际皮肤淋巴瘤学会/欧洲癌症研究与治疗组织分期建议的验证。
J Clin Oncol. 2010 Nov 1;28(31):4730-9. doi: 10.1200/JCO.2009.27.7665. Epub 2010 Sep 20.
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T-cell lymphoma of the upper eyelid: a case report and review of the literature.上睑T细胞淋巴瘤:一例报告并文献复习
Surg Oncol. 2006 Nov;15(3):135-9. doi: 10.1016/j.suronc.2006.11.001. Epub 2006 Dec 19.
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WHO-EORTC classification for cutaneous lymphomas.世界卫生组织-欧洲癌症研究与治疗组织皮肤淋巴瘤分类
Blood. 2005 May 15;105(10):3768-85. doi: 10.1182/blood-2004-09-3502. Epub 2005 Feb 3.
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Surgical treatment of obstructive palpebral tumors in d'emblee variant of cutaneous T-cell lymphoma.皮肤T细胞淋巴瘤突发变异型中阻塞性睑部肿瘤的外科治疗
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Reverse radial forearm fascial flap for soft tissue coverage of hand and forearm wounds.逆行桡侧前臂筋膜瓣用于手部和前臂伤口的软组织覆盖。
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Primary cutaneous T-cell lymphoma: review and current concepts.原发性皮肤T细胞淋巴瘤:综述与当前概念
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Osteocutaneous radial forearm flap for hand reconstruction.用于手部重建的桡骨前臂骨皮瓣
J Hand Surg Am. 1999 May;24(3):594-603. doi: 10.1053/jhsu.1999.0594.
9
Transformation of mycosis fungoides/Sezary syndrome: clinical characteristics and prognosis.蕈样肉芽肿/赛塞里综合征的转化:临床特征与预后
Blood. 1998 Aug 15;92(4):1150-9.
10
The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy.肢体软组织肉瘤的治疗:(1)保肢手术联合放射治疗与截肢术的前瞻性随机评估,以及(2)辅助化疗的作用。
Ann Surg. 1982 Sep;196(3):305-15. doi: 10.1097/00000658-198209000-00009.