Survey of susceptibility to marbofloxacin in bacteria isolated from diseased pigs in Europe.

A monitoring programme of marbofloxacin susceptibility of bacteria from Europe causing respiratory tract infection and meningitis in pigs has been active since 1994 and 2002, respectively. Monitoring digestive, metritis and urinary tract infection (UTI) in pigs has been active since 2005 and susceptibility results until 2013 are presented. Minimum inhibitory concentration (MIC) was determined by broth microdilution. For MIC interpretation, Vétoquinol-evaluated breakpoints were applied. For digestive pathogens, and species (1717 and 300 isolates, respectively) exhibited 7.5 per cent resistance in and no resistance in species. Similarly, from metritis (369 isolates) had 7.0 per cent resistance to marbofloxacin. However, from UTI (633 isolates) had higher resistance (10.4 per cent). For causing meningitis (585 isolates), marbofloxacin susceptibility was very high with only 0.5 per cent resistance and 0.4 per cent resistance was observed with causing respiratory disease (729 isolates). Other respiratory pathogens were also highly susceptible to marbofloxacin with no resistance in (647 isolates) or (504 isolates), 0.1 per cent resistance in (1373 isolates) and 1.4 per cent resistance in (145 isolates). There was no apparent change in marbofloxacin MIC over time for any bacterial pathogen based on MIC These data confirm previously published MIC results from porcine and other animal infections.