Núñez-Núñez María, Navarro María Dolores, Gkolia Panagiota, Babu Rajendran Nithya, Del Toro María Dolores, Voss Andreas, Sharland Mike, Sifakis Frangiscos, Tacconelli Evelina, Rodríguez-Baño Jesús
Unit of Infectious Disease, Microbiology, and Preventive Medicine, Institute of Biomedicine of Seville (IBIS)/University Hospital Virgen Macarena-Virgen del Rocío/Spanish National Research Council (CSIC), Seville, Spain.
Departamento de Medicina, Universidad de Sevilla, Seville, Spain.
BMJ Open. 2017 Mar 27;7(3):e014538. doi: 10.1136/bmjopen-2016-014538.
The worldwide spread of antimicrobial resistance is now recognised as a global public health threat. Owing to the geographical heterogeneity, complexity and continuously evolving dynamics of resistant organisms and genes, surveillance is a key tool for understanding, measuring and informing actions in the fight against this problem. To date there is no harmonisation of key indicators or of methodologies used to obtain them.
The main objective of this project is to systematically review and analyse the current publicly available surveillance activities on antimicrobial resistance and healthcare-associated infections in Europe. Eligible activities are those endorsed by regional, national or transnational health organisations and scientific societies providing data on a periodic basis. Grey and peer-reviewed literature will be searched with no language restrictions. Three independent reviewers will perform a two-step selection process using a previously piloted, tailored electronic data extraction form. Descriptive summaries and tables of all relevant findings will be performed and reported according to PRISMA guidelines.
We did not seek ethical approval for this study because the data to be collected are not linked to individuals. Data will be presented at international conferences and published in peer-reviewed journals.
CRD42016033867.
抗菌药物耐药性在全球范围内的传播现已被公认为是对全球公共卫生的威胁。由于耐药生物和基因存在地理异质性、复杂性以及不断演变的动态变化，监测是了解、衡量和指导应对这一问题行动的关键工具。迄今为止，关键指标或用于获取这些指标的方法尚未统一。
本项目的主要目标是系统回顾和分析欧洲目前关于抗菌药物耐药性和医疗保健相关感染的公开监测活动。符合条件的活动是那些得到区域、国家或跨国卫生组织及科学协会认可并定期提供数据的活动。将检索灰色文献和经同行评审的文献，无语言限制。三名独立评审员将使用预先试点的、量身定制的电子数据提取表进行两步筛选过程。将根据PRISMA指南对所有相关研究结果进行描述性总结并制表报告。
本研究未寻求伦理批准，因为要收集的数据与个人无关。数据将在国际会议上展示并发表在经同行评审的期刊上。
CRD42016033867。
