Bernstein S A, Reuter V E, Carroll P R, Whitmore W F
Department of Surgery (Urologic Service), Memorial Sloan-Kettering Cancer Center, New York, New York.
Urology. 1988 May;31(5):432-6. doi: 10.1016/0090-4295(88)90744-3.
A case of primary signet-ring cell carcinoma of the urinary bladder is described clinically and pathologically. In this rare neoplasm the characteristic cells contain large amounts of cytoplasmic mucin which compresses the nucleus to one side. This tumor demonstrates nicely the ability of bladder epithelium to undergo metaplasia. Most previously described cases have pursued a relentlessly progressive and fatal course despite varied forms of therapy.
本文从临床和病理方面描述了一例原发性膀胱印戒细胞癌。在这种罕见的肿瘤中，特征性细胞含有大量细胞质黏液，将细胞核挤压至一侧。该肿瘤很好地展示了膀胱上皮发生化生的能力。尽管采用了多种治疗方法，但大多数先前报道的病例仍呈持续进展并最终致命。
