Moodley Anand A, Dlwati Mahlubonke S, Durand Miranda
Department of Neurology, Greys Hospital, Pietermaritzburg, South Africa; Department of Neurology, University of KwaZulu-Natal, Durban, South Africa.
Department of Neurology, Greys Hospital , Pietermaritzburg, South Africa.
Neuroophthalmology. 2016 Dec 20;41(2):84-89. doi: 10.1080/01658107.2016.1258581. eCollection 2017 Apr.
The role of the optic canal in the pathogenesis of papilloedema has been under scrutiny recently. Whether a larger canal precedes more severe papilloedema or is the result of bone remodelling from chronically raised pressure across a pressure gradient is not clear. The authors present the magnetic resonance imaging findings of a 29-year-old female with fulminant and untreated idiopathic intracranial hypertension. Imaging showed focal expansion and intrinsic signal changes of the intracanalicular optic nerve. The authors discuss the possibility of either fluid accumulation within the optic nerves from a water hammer effect across blocked optic canals resulting from the steep pressure gradient or opticomalacia (optic nerve softening) from chronic ischaemia.
视神经管在视乳头水肿发病机制中的作用最近受到了密切关注。尚不清楚较宽大的神经管是先于更严重的视乳头水肿出现,还是慢性压力升高通过压力梯度导致骨重塑的结果。作者展示了一名29岁患有暴发性且未经治疗的特发性颅内高压女性的磁共振成像结果。成像显示管内段视神经有局灶性扩张和信号改变。作者讨论了两种可能性,一是由于陡峭的压力梯度导致视神经管阻塞,水击效应使视神经内液体蓄积;二是慢性缺血导致视神经软化。