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CT测量的视神经管尺寸会影响特发性颅内高压患者的视乳头水肿程度和视觉功能障碍吗?

Do Optic Canal Dimensions Measured on CT Influence the Degree of Papilloedema and Visual Dysfunction in Idiopathic Intracranial Hypertension?

作者信息

Skipper Nicholas T, Igra Mark S, Littlewood Revelle, Armitage Paul, Laud Peter J, Mollan Susan P, Sharrack Basil, Pepper Irene M, Batty Ruth, Connolly Daniel J A, Hickman Simon J

机构信息

Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK.

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

Neuroophthalmology. 2018 Jun 26;43(1):3-9. doi: 10.1080/01658107.2018.1483406. eCollection 2019 Feb.

Abstract

A recent study found that increased optic canal area on magnetic resonance imaging was associated with worse papilloedema in idiopathic intracranial hypertension (IIH). We repeated this study using more accurate computerized tomography derived measurements. Optic canal dimensions were measured from 42 IIH patients and 24 controls.  These were compared with papilloedema grade.  There was no correlation between any of the optic canal measurements and papilloedema grade and no significant difference in optic canal measurements between patients and controls. Our results cast doubt on the existing literature regarding the association between optic canal size and the degree of papilloedema in IIH. CT delineates bony anatomy more accurately than MRI and our CT-derived optic canal measurements cast doubt on the existing literature regarding the association between optic canal size and the degree of Papilloedema in IIH.

摘要

最近一项研究发现,在特发性颅内高压(IIH)患者中,磁共振成像显示的视神经管面积增加与更严重的视乳头水肿相关。我们使用更精确的计算机断层扫描测量方法重复了这项研究。从42例IIH患者和24例对照者中测量视神经管尺寸,并将其与视乳头水肿分级进行比较。视神经管的任何测量值与视乳头水肿分级之间均无相关性,患者与对照者的视神经管测量值也无显著差异。我们的结果对现有关于IIH患者视神经管大小与视乳头水肿程度之间关联的文献提出了质疑。计算机断层扫描(CT)比磁共振成像(MRI)更能准确描绘骨骼解剖结构,我们通过CT得出的视神经管测量结果对现有关于IIH患者视神经管大小与视乳头水肿程度之间关联的文献提出了质疑。

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Cup-to-Disc Ratio in Idiopathic Intracranial Hypertension without Papilloedema.无视乳头水肿的特发性颅内高压患者的杯盘比
Neuroophthalmology. 2014 Feb 25;38(2):69-73. doi: 10.3109/01658107.2013.874452. eCollection 2014.

本文引用的文献

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Pathogenesis of optic disc edema in raised intracranial pressure.颅内压升高时视盘水肿的发病机制。
Prog Retin Eye Res. 2016 Jan;50:108-44. doi: 10.1016/j.preteyeres.2015.10.001.
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Compartmentalized cerebrospinal fluid.分隔的脑脊液
Int Ophthalmol Clin. 2014 Winter;54(1):95-102. doi: 10.1097/IIO.0000000000000010.
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The optic nerve: a new window into cerebrospinal fluid composition?视神经:了解脑脊液成分的新窗口?
Brain. 2006 Apr;129(Pt 4):1027-30. doi: 10.1093/brain/awl045. Epub 2006 Feb 27.

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