Sharif Dawod, Sharif-Rasslan Amal, Shahla Camilia, Rosenschein Uri
Department of Cardiology, Bnai Zion Medical Center, Israel; Technion - Israel Institute of Technology, Haifa, Israel.
Technion - Israel Institute of Technology, Haifa, Israel.
Cardiol Res. 2011 Feb;2(1):36-41. doi: 10.4021/cr7w. Epub 2011 Jan 20.
Mitral annular systolic displacement from M-mode echocardiography and velocity from tissue Doppler imaging reflect subendocardial longitudinal systolic LV performance and may precede radial abnormalities. The aim of this study is to evaluate the utility of mitral annular systolic displacement (D) and velocity (V) during dobutamine stress echocardiography (DSE) in detecting left ventricular (LV) functional reserve and wall motion abnormality (WMA).
Fifty-nine subjects, 15 with resting WMA, underwent DSE and measurement of mitral systolic (D) and (V) before and immediately after DSE. Annular septal (D) was lower in those with WMA than in those without, at rest 10.5 ± 4 cm versus 13.2 ± 2 cm, = 0.015, and after DSE, 11.7 ± 3.8 cm versus 14 ± 2.25 cm, = 0.036, but without significant change after stress. Annular systolic (V) at rest with WMA was 9.7 ± 1.8 cm/sec and similar to those without, 11.25 ± 2.7 cm/sec. In both groups the velocity increased after DSE, 14.5 ± 4.5 cm/sec, = 0.025 with WMA and 17.8 ± 3.2 cm/sec, = 1.99 x 10 in those without WMA. Velocities after DSE were lower in those with WMA, = 2.25 x 10.
To evaluate LV systolic performance mitral annular systolic longitudinal displacement is valuable at rest, but for assessment of LV functional reserve after stress velocities are better.
M 型超声心动图测得的二尖瓣环收缩期位移及组织多普勒成像测得的速度反映心内膜下纵向收缩期左心室功能,且可能早于径向异常。本研究旨在评估多巴酚丁胺负荷超声心动图(DSE)期间二尖瓣环收缩期位移(D)和速度(V)在检测左心室(LV)功能储备和室壁运动异常(WMA)方面的效用。
59 名受试者,其中 15 名有静息 WMA,接受了 DSE 检查,并在 DSE 前及检查后立即测量二尖瓣收缩期(D)和(V)。有 WMA 者的室间隔环(D)在静息时低于无 WMA 者,分别为 10.5±4cm 与 13.2±2cm,P = 0.015,DSE 后分别为 11.7±3.8cm 与 14±2.25cm,P = 0.036,但负荷后无显著变化。有 WMA 者静息时二尖瓣环收缩期(V)为 9.7±1.8cm/秒,与无 WMA 者的 11.25±2.7cm/秒相似。两组在 DSE 后速度均增加,有 WMA 者为 14.5±4.5cm/秒,P = 0.025,无 WMA 者为 17.8±3.2cm/秒,P = 1.99×10⁻⁵。有 WMA 者 DSE 后的速度较低,P = 2.25×10⁻⁵。
为评估左心室收缩功能,二尖瓣环收缩期纵向位移在静息时很有价值,但对于评估负荷后左心室功能储备,速度指标更好。