Sharif Dawod, Sharif-Rasslan Amal, Shahla Camilia
Department of Cardiology, Bnai Zion Medical Center, Haifa, Israel; Technion - Israel Institute of Technology, Haifa, Israel.
Technion - Israel Institute of Technology, Haifa, Israel.
Cardiol Res. 2011 Feb;2(1):16-26. doi: 10.4021/cr14w. Epub 2011 Jan 20.
Longitudinal systolic left ventricular contraction is complementary to the radial performance and can be assessed using tissue Doppler imaging (TDI). This study was performed to evaluate the contribution of mitral annular systolic velocities using TDI after dobutamine stress echocardiography (DSE).
Fifty subjects with suspected coronary artery disease and chest pain were examined, using DSE as usual, as well as TDI imaging of the mitral annulus at the septal, lateral, inferior, anterior, posterior regions and the proximal anteroseptal region from the apical views, before and immediately after DSE. In 24 subjects the study was normal, while wall motion abnormality was seen in 26, 9 of them only after DSE. Mitral annular systolic velocity at the 6 locations increased significantly after DSE both in normal subjects and in those with wall motion abnormality (WMA). After DSE mitral annular septal systolic velocity in normals, 19.2 ± 3.8 cm/sec, was higher than in those with WMA, 14.6 ± 2.5 cm/sec, P < 0.0003. Post-DSE mitral systolic velocity was senstive and accurate in predicting WMA.
Systolic mitral TDI velocities increase after DSE, however to a lesser extent in those with wall motion abnormality, and can differentiate them from normal subjects.
左心室纵向收缩与径向功能互补，可通过组织多普勒成像（TDI）进行评估。本研究旨在评估多巴酚丁胺负荷超声心动图（DSE）后使用TDI测量二尖瓣环收缩速度的作用。
对50例疑似冠心病且有胸痛症状的患者进行检查，像往常一样进行DSE，并在DSE前后从心尖视图对二尖瓣环的间隔、侧壁、下壁、前壁、后壁区域以及近端前间隔区域进行TDI成像。24例患者检查结果正常，26例有室壁运动异常，其中9例仅在DSE后出现异常。正常受试者和室壁运动异常（WMA）患者在DSE后，6个部位的二尖瓣环收缩速度均显著增加。DSE后，正常受试者二尖瓣环间隔收缩速度为19.2±3.8cm/秒，高于WMA患者的14.6±2.5cm/秒，P<0.0003。DSE后二尖瓣收缩速度在预测WMA方面具有敏感性和准确性。
DSE后二尖瓣TDI收缩速度增加，但室壁运动异常患者增加幅度较小，且可将其与正常受试者区分开来。
