在其他方面健康的成年人中发生的自体瓣膜感染性心内膜炎。
native valve infective endocarditis in an otherwise healthy adult.
作者信息
Ikediobi Uchenna, Sutton Richard E
机构信息
Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine , New Haven, CT 6520 , USA.
出版信息
JMM Case Rep. 2016 Feb 18;3(1):e005018. doi: 10.1099/jmmcr.0.005018. eCollection 2016 Feb.
INTRODUCTION
Fungal endocarditis is a rare cause of infective endocarditis, and spp. account for up to 30 % of all cases. Risk factors include intravenous drug use, immunosuppression, malignancy and the presence of prosthetic valves.
CASE PRESENTATION
We present a case of endocarditis in a patient without any known or described risk factors.
CONCLUSION
Diagnosis of endocarditis requires a high clinical index of suspicion, given the initial non-specific presentation, and treatment may require both medical and surgical therapies to ensure improved outcomes, but mortality rates still approach 80 %. Voriconazole remains the antifungal agent of choice.
引言
真菌性心内膜炎是感染性心内膜炎的罕见病因，某菌种占所有病例的比例高达30%。危险因素包括静脉药物使用、免疫抑制、恶性肿瘤以及人工瓣膜的存在。
病例介绍
我们报告一例无任何已知或描述的危险因素的患者发生的某心内膜炎病例。
结论
鉴于最初的非特异性表现，某心内膜炎的诊断需要高度的临床怀疑指数，治疗可能需要药物和手术治疗以确保改善预后，但死亡率仍接近80%。伏立康唑仍然是首选的抗真菌药物。
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