Infectious Diseases, Emory University, 206 Woodruff Research Extension Bldg, 49 Jesse Hill Jr. Drive, Atlanta, GA 30303, USA.
Int J Infect Dis. 2010 Dec;14(12):e1040-7. doi: 10.1016/j.ijid.2010.08.005. Epub 2010 Oct 29.
We present a case of cardiac device-related Aspergillus endocarditis in a patient with a pacemaker and an allogeneic bone marrow transplant to segue into a review of the Aspergillus endocarditis literature. Aspergillus endocarditis should be suspected in patients with underlying immunosuppression, negative cultures, and a vegetation on echocardiography. Diagnosis ultimately requires confirmation by tissue histology and culture. The optimal treatment approach often requires aggressive surgical debridement in conjunction with prolonged antifungal therapy.
我们报告了一例心脏器械相关的曲霉菌心内膜炎病例，该患者有起搏器和同种异体骨髓移植，接着对曲霉菌心内膜炎文献进行了回顾。对于有潜在免疫抑制、阴性培养和超声心动图上有赘生物的患者，应怀疑曲霉菌心内膜炎。最终诊断需要通过组织病理学和培养来确认。最佳治疗方法通常需要积极的手术清创术，同时结合长期抗真菌治疗。
