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成人致命性侵袭性脑膜炎球菌病的延迟诊断

Delayed recognition of fatal invasive meningococcal disease in adults.

作者信息

Nagel Frederick W, Ezeoke Ifeoma, Antwi Mike, Del Rosso Paula E, Dorsinville Marie, Isaac Beth M, Hayden Althea, Hoffman Robert S, Weingart Scott D, Weiss Don

机构信息

Department of Emergency Medicine, North Central Bronx Hospital, Albert Einstein College of Medicine , Bronx, NY , United States.

New York City Department of Health and Mental Hygiene , New York, NY , United States.

出版信息

JMM Case Rep. 2016 Jun 28;3(3):e005027. doi: 10.1099/jmmcr.0.005027. eCollection 2016 Jun.

DOI:10.1099/jmmcr.0.005027
PMID:28348753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5330221/
Abstract

INTRODUCTION

Invasive meningococcal disease can be difficult to detect early in its course when patients may appear well and the severity of their illness is obscured by non-specific complaints.

CASE PRESENTATION

We report five cases of meningococcal sepsis in adult patients who presented to an emergency department early in the course of their disease, but whose severity of illness was not recognized.

CONCLUSION

Suspicion of meningococcal sepsis should be heightened in the setting of hypotension, tachycardia, elevated shock index, leukopaenia with left shift, thrombocytopaenia and hypokalaemia, prompting early sepsis care.

摘要

引言

侵袭性脑膜炎球菌病在病程早期可能难以检测到,因为患者可能看起来状况良好,且非特异性症状掩盖了病情的严重程度。

病例报告

我们报告了5例成年脑膜炎球菌败血症患者,他们在疾病早期到急诊科就诊,但病情严重程度未被识别。

结论

在出现低血压、心动过速、休克指数升高、白细胞减少伴左移、血小板减少和低钾血症的情况下,应提高对脑膜炎球菌败血症的怀疑,促使早期进行败血症治疗。

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Community-Based Outbreak of Neisseria meningitidis Serogroup C Infection in Men who Have Sex with Men, New York City, New York, USA, 2010-2013.2010 - 2013年美国纽约市男男性行为者中基于社区的C群脑膜炎奈瑟菌感染暴发
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Utility of the shock index in patients with sepsis.休克指数在脓毒症患者中的应用价值。
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Shock index and early recognition of sepsis in the emergency department: pilot study.休克指数与急诊脓毒症早期识别:一项初步研究。
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Lancet. 2006 Feb 4;367(9508):397-403. doi: 10.1016/S0140-6736(06)67932-4.
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