Kuchibiro Tomokazu, Ikeda Takeshi, Nakanishi Hirotaka, Morishita Yukiko, Houdai Katsuyuki, Ito Junko, Gonoi Tohru
Department of Clinical Laboratory, Naga Municipal Hospital, 1282 Uchita, Kinokawa, Wakayama, 649-6414, Japan.
Department of Respiratory Medicine, Naga Municipal Hospital, 1282 Uchita, Kinokawa, Wakayama, 649-6414, Japan.
JMM Case Rep. 2016 Aug 30;3(4):e005054. doi: 10.1099/jmmcr.0.005054. eCollection 2016 Aug.
species usually cause opportunistic infections, and the frequency of these infections is increasing owing to the growing population of immunocompromised hosts. However, species may sometimes cause an infection disease in immunocompetent hosts. infections are the least common and are very rare.
Herein, we report the first case of a pulmonary infection with in a 61-year-old Japanese woman with a history of hyperlipidaemia and bronchiectasis and a 6-month history of non-productive hacking cough. A sample of bronchial lavage fluid obtained by bronchofiberscopy showed filamentous branching gram-positive rods and acid-fast filamentous branching rods, and a colony of suspected was cultured. Based on 16S rRNA, , and gene sequence analyses and biochemical and physiological properties, the strain was identified as The strain was resistant to the antimicrobial agents amoxicillin-clavulanic acid, clarithromycin, minocycline, gentamycin, tobramycin, ciprofloxacin and trimethoprim-sulfamethoxazole. The patient was treated with biapenem followed by intravenous amikacin and oral linezolid.
Despite its rarity, the species require attention owing to the existence of multidrug-resistant strains.
[物种名称]通常引起机会性感染，由于免疫功能低下宿主群体的增加，这些感染的频率正在上升。然而，[物种名称]有时可能在免疫功能正常的宿主中引起感染性疾病。[具体感染类型]感染是最不常见的，而且非常罕见。
在此，我们报告首例61岁日本女性发生[物种名称]肺部感染的病例，该女性有高脂血症和支气管扩张病史，干咳无痰6个月。通过纤维支气管镜获得的支气管灌洗液样本显示丝状分支革兰氏阳性杆菌和抗酸丝状分支杆菌，并培养出疑似[物种名称]的菌落。基于16S rRNA、[相关基因名称1]、[相关基因名称2]和[相关基因名称3]基因序列分析以及生化和生理特性，该菌株被鉴定为[物种名称]。该菌株对阿莫西林-克拉维酸、克拉霉素、米诺环素、庆大霉素、妥布霉素、环丙沙星和甲氧苄啶-磺胺甲恶唑等抗菌药物耐药。患者先接受比阿培南治疗，随后静脉注射阿米卡星和口服利奈唑胺。
尽管罕见，但由于存在多重耐药菌株，[物种名称]需要引起关注。
