He Longwei, Yang Xueling, Xu Kaixin, Lin Weiying
Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Shandong 250022, P. R. China.
Chem Commun (Camb). 2017 Apr 6;53(29):4080-4083. doi: 10.1039/c7cc00512a.
The mitochondria-targeted turn-on fluorescent probe (Mito-FMP) based on a benzoxadiazole platform was developed for detection of malondialdehyde (MDA). Mito-FMP performed with large enhancement of the optical signal (774-fold) in response to MDA in an aqueous system and has the capability of monitoring endogenous MDA in HeLa cells and onion tissues.
基于苯并恶二唑平台开发了一种用于检测丙二醛（MDA）的线粒体靶向开启型荧光探针（Mito-FMP）。Mito-FMP在水体系中对MDA响应时光学信号大幅增强（774倍），并且能够监测HeLa细胞和洋葱组织中的内源性MDA。
