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脓毒症患者心房颤动的发病率及预后

Incidence and Prognosis of Atrial Fibrillation in Patients With Sepsis.

作者信息

Wells Gretchen L, Morris Peter E

机构信息

Department of Internal Medicine-Section on Cardiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, USA.

Department of Internal Medicine-Section on Pulmonary/Critical Care, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, USA.

出版信息

Cardiol Res. 2011 Dec;2(6):293-297. doi: 10.4021/cr108w. Epub 2011 Nov 20.

DOI:10.4021/cr108w
PMID:28352398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5358258/
Abstract

BACKGROUND

Although the mortality rate among patients with sepsis is declining, the incidence of both sepsis and sepsis-related deaths is increasing, likely due to its presence in a growing elderly population. As atrial fibrillation is more common in the elderly, we hypothesize that its presence will be associated with greater mortality among patients with sepsis.

METHODS

The Medical Intensive Care Unit (MICU) database of a large tertiary care medical center was queried for sepsis-related codes and atrial fibrillation.

RESULTS

Atrial fibrillation was associated with older age and a higher mortality in this series of patients with sepsis.

CONCLUSIONS

Whether atrial fibrillation is a marker of disease severity or contributes to mortality is uncertain. Further studies are necessary to determine optimal management.

摘要

背景

尽管脓毒症患者的死亡率正在下降,但脓毒症及其相关死亡的发生率却在上升,这可能是由于老年人口不断增加所致。由于心房颤动在老年人中更为常见,我们推测其存在将与脓毒症患者更高的死亡率相关。

方法

查询了一家大型三级医疗中心的医学重症监护病房(MICU)数据库,以获取与脓毒症相关的编码和心房颤动信息。

结果

在这一系列脓毒症患者中,心房颤动与年龄较大和较高的死亡率相关。

结论

心房颤动是疾病严重程度的标志物还是导致死亡率升高尚不确定。需要进一步研究以确定最佳治疗方案。

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Paroxysmal atrial fibrillation in critically ill patients with sepsis.脓毒症重症患者的阵发性心房颤动
J Intensive Care Med. 2008 May-Jun;23(3):178-83. doi: 10.1177/0885066608315838. Epub 2008 Apr 28.
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Clinical review: treatment of new-onset atrial fibrillation in medical intensive care patients--a clinical framework.临床综述:医学重症监护患者新发房颤的治疗——一个临床框架
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