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依维莫司洗脱支架植入左前降支冠状动脉开口病变后的一年结局

One-Year Outcomes After Everolimus-Eluting Stents Implantation in Ostial Lesions of Left Anterior Descending Coronary Arteries.

作者信息

Golmohamadi Zahra, Sokhanvar Sepideh, Aslanabadi Naser, Ghaffari Samad, Sohrabi Bahram

机构信息

Cardiovascular Research Center, Shaheed Madani Heart Hospital, Medical Science University, Tabriz, Iran.

Ayatollah Mosavi Cardiology Department, Medical Science University, Zanjan, Iran.

出版信息

Cardiol Res. 2013 Dec;4(6):192-198. doi: 10.4021/cr295w. Epub 2014 Jan 2.

Abstract

BACKGROUND

In recent years, stents are increasingly used in variety of coronary lesions. Ostial lesion of left anterior descending coronary artery (LAD) however remains a challenge area because of the invariable involvement of distal left main coronary artery (LMCA). This study was designed to evaluate the clinical and angiographic outcomes of everolimus-eluting stent (EES) implantation for ostial LAD.

METHODS

EESs were implanted in 45 consecutive patients with ostial LAD stenoses. For complete lesion coverage, stent positing was extended into the distal LMCA in 6 patients (13.3%) with intermediated LMCA narrowing. We assess MACE during one-year follow-up.

RESULTS

In-hospital success rate was 100%; neither cardiac death nor stent thrombosis in our patients, but two patients had myocardial infarction in non-related coronary artery during follow-up. Two patients had angiographic restenosis and underwent TLR. The cumulative MACE-free survival rate was 95.6% at one year.

CONCLUSION

EES was in ostial LAD lesions with complete lesion coverage achieving high procedural success rate and acceptable clinical outcomes during one-year follow-up period.

摘要

背景

近年来,支架越来越多地应用于各种冠状动脉病变。然而,由于左冠状动脉主干(LMCA)远端总是受累,左前降支冠状动脉(LAD)开口病变仍然是一个具有挑战性的领域。本研究旨在评估依维莫司洗脱支架(EES)植入治疗LAD开口病变的临床和血管造影结果。

方法

连续45例LAD开口狭窄患者植入EES。为了完全覆盖病变,6例(13.3%)LMCA中度狭窄患者的支架位置延伸至LMCA远端。我们评估了一年随访期间的主要不良心血管事件(MACE)。

结果

住院成功率为100%;我们的患者中既没有心源性死亡也没有支架血栓形成,但有2例患者在随访期间非相关冠状动脉发生心肌梗死。2例患者发生血管造影再狭窄并接受了靶病变血运重建(TLR)。一年时累积无MACE生存率为95.6%。

结论

EES用于LAD开口病变且病变完全覆盖时,在一年随访期内可实现较高的手术成功率和可接受的临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0609/5358308/0df509b0e986/cr-04-192-g001.jpg

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